1142945-83-2

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
7H-Pyrrolo[2,3-d]pyrimidin-2-amine, 4-chloro-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]is used as a chemical compound in pharmaceutical research and drug development for its potential biological activities and unique molecular structure. Further scientific research and experimentation are required to explore its specific properties and applications in the development of new therapeutic agents.

Upstream product

• 1143571-96-3 tert-butyl [(1Z)-[(tert-butoxycarbonyl)amino]{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}methylidene]carbamate 
• 52133-67-2 ethyl 2-cyano-4,4-diethoxybutyrate 
• 50609-01-3 4-(2-pyrrolidinoethoxy)aniline 
• 1142945-82-1 2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-7H-pyrrolo[2,3-d]pyrimidin-4-ol 

Downstream Products

• 1142946-66-4 N-tert-butyl-3-methyl-5-(2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)thiophene-2-carboxamide 
• 1147015-03-9 1-isopropyl-7-((2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)ethynyl)-1H-indole-3-carbonitrile 
• 1147015-23-3 4-{[2-methyl-1-(1-methylethyl)-1H-benzimidazol-7-yl]ethynyl}-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine 
• 1147015-28-8 4-{[2-ethyl-1-(1-methylethyl)-1H-benzimidazol-7-yl]ethynyl}-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine 
• 1147015-00-6 4-((2-isopropylphenyl)ethynyl)-N-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine 
• 1142946-33-5 2-{2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-benzo[b]thiophene-6-carbonitrile 
• 1142946-52-8 5-(2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-methylthiophene-2-carbonitrile 
• 1142947-11-2 tert-butyl 2-(2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate 
• 1142945-85-4 (5-{2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-thiophen-2-yl)-methanol 
• 1142946-13-1 5-{2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-thiophene-2-carbaldehyde 
• 1142945-84-3 [4-(5-chloro-thiophen-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine 

Relevant academic research and scientific papers

PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME

Provided herein are pyrrolopyrimide alkynyl compounds, and methods of making and using the same. Such compounds may be used in inflammatory or myeloproliferative disorders. The disclosure also provides for treating cancer.

PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS

Provided herein are pyrrolopyrimidine compounds of Formula (I) wherein R1 is a heteroaryl containing at least one S atom, and optionally substituted on a ring carbon by one, two, or three substituents each independently selected from the group consisting of : halo, hydroxyl, nitro, formyl, formamido, cyano, sulfonyl, carboxy, amino, amido, acylamino, carbamoyl, sulphamoyl, alkyl, alkenyl, CF3, ureido, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, carbaldehyde oxime, N -alkylsulphamoyl, N-alkylcarbamoyl, -OR13R11 or -R13R11; R2 is phenyl or pyridinyl, wherein R2 optionally substituted on a ring carbon by one, two, or three substituents each indenpendently selected from the group consisting of : halo, hydroxyl, cyano, nitro, formyl, formamido, carboxy, sulfonyl, amino, amido, -N- alkyl -amino, carbamoyl, sulphamoyl, CF3, ureido, alkyl, alkenyl, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, N-alkylsulphamoyl, N-alkylcarbamoyl, -OR11, -OR12R11, or -R12R11; and methods of making and using the same. Such compounds may be used in inflammatory or myeloproliferative disorders. The disclosure also provides for treating cancer.