1143-11-9 Usage
Uses
Used in Traditional and Modern Medicine:
2,3,5,6,8-Pentahydroxy-1,4-naphthoquinone is used as an antimicrobial and anti-inflammatory agent for its ability to inhibit the growth of fungi and other microorganisms, as well as to reduce inflammation in the body.
Used in Anticancer Applications:
2,3,5,6,8-Pentahydroxy-1,4-naphthoquinone is used as a potential anticancer agent, as it has been found to exhibit activities that may help in the prevention and treatment of cancer.
Used in Antioxidant Applications:
2,3,5,6,8-Pentahydroxy-1,4-naphthoquinone is used as an antioxidant, helping to protect cells from damage caused by free radicals and oxidative stress.
Used in Agriculture:
2,3,5,6,8-Pentahydroxy-1,4-naphthoquinone is used as an allelopathic agent to inhibit the growth of other plants, which can be beneficial in controlling weed growth and promoting the growth of desired plant species.
Used in Drug Delivery Systems:
2,3,5,6,8-Pentahydroxy-1,4-naphthoquinone is used in the development of drug delivery systems to improve the bioavailability and therapeutic outcomes of various medications, particularly in the context of cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 1143-11-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,4 and 3 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1143-11:
(6*1)+(5*1)+(4*4)+(3*3)+(2*1)+(1*1)=39
39 % 10 = 9
So 1143-11-9 is a valid CAS Registry Number.
1143-11-9Relevant academic research and scientific papers
Balaneva,Shestak,Anufriev,Novikov
, p. 213 - 217 (2016)
The sea-urchin metabolite spinochrome D (1) was synthesized in 58% overall yield via oxidation of 2,3-dichloronaphthazarin (13) into 2-hydroxy-6,7-dichloronaphthazarin (14), O-methylation of 14, nucleophilic substitution by MeO groups of the Cl atoms in the resulting 2-methoxy-6,7-dichloronaphthazarin (19), and hydrolysis of the obtained 2,3,6-trimethoxynaphthazarin (10).
Sabutskii, Yuri E.,Denisenko, Vladimir A.,Polonik, Sergey G.
, p. 3738 - 3748 (2018)
A series of substituted 2-alkoxy-1,4-naphthoquinone derivatives were obtained by acid-catalyzed condensation of substituted 2-hydroxy-1,4-naphthoquinones with propan-1-ol, butan-1-ol, or pentan-1-ol in good yields. Based on this reaction a versatile preparative synthesis of spinochrome D was developed.
