114311-32-9 Usage
Description
Different sources of media describe the Description of 114311-32-9 differently. You can refer to the following data:
1. Imazamox (2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5- (methoxymethyl)-3-pyridinecarboxylic acid) is a systemic herbicide that moves throughout the plant tissue and prevents plants from producing a necessary enzyme, acetolactate synthase (ALS), which is not found in animals. Susceptible plants will stop growing soon after treatment, but plant death and decomposition will occur over several weeks.
Imazamox is used for the control of vegetation in and around aquatic sites and terrestrial non-crop sites. It is herbicidally active on many submerged, emergent, and floating broadleaf and monocot aquatic plants in and around standing and slow- moving water bodies. It is used as herbicide on sunflower seed, alfalfa, oilseed rape and soya bean seed and used for the control of most annual and perennial broadleaf weeds and grasses, woody species, and riparian and emergent aquatic weed species.
Imazamox is only moderately persistent, and it degrades aerobically in the soil to a non-herbicidal metabolite which is immobile or moderately mobile. Imazamox also degrades by aqueous photolysis.
2. Imazamox is registered throughout the world for use
in leguminous crops, including soybeans, alfalfa, and
edible beans, as well as in imidazolinone-resistant
crops (9). A nonionic surfactant or oil adjuvant is
required for maximum activity. Imazamox
is much more active when applied post-emergent to the
weeds compared with pre-emergence application (9). One
difference between imazamox and other imidazolinones is
the much shorter interval needed before sensitive follow
crops can be planted. This difference is due to the more
rapid degradation of imazamox in the soil compared with
other imidazolinones.
References
[1] http://dnr.wi.gov/lakes/plants/factsheets/ImazamoxFactsheet.pdf
[2] https://www.efsa.europa.eu/en/efsajournal/pub/4432
[3] http://www.mass.gov/eea/docs/agr/pesticides/aquatic/imazamox.pdf
Chemical Properties
Off-White Solid
Uses
Different sources of media describe the Uses of 114311-32-9 differently. You can refer to the following data:
1. Imazamox is an imidazolinone based acetolactate synthase inhibitor that is utilized as a herbicide for weed control.
2. Herbicide.
Pharmacology
Imazamox kills plants by inhibiting acetolactate synthase
(ALS) (I50 = 1 μM), which is the first common enzyme in
the biosynthesis of the branched chain amino acids, valine,
leucine, and isoleucine. Imazamox is rapidly absorbed
through the leaves of plants. Once it enters the plant,
imazamox rapidly translocates to the growing points and
growth ceases within 1 day after herbicide application,
followed by chlorosis and then by necrosis of the growing
points. Total plant death will occur within 2 to 3 weeks
after treatment.
Metabolism
Plant Metabolism. The selectivity of imazamox is due to
differential rates and routes of metabolism in tolerant
crops versus susceptible weeds (10). The primary
metabolic route is hydroxylation followed by conjugation
to glucose. In imidazolinone-resistant crops, the primary
mechanism of selectivity is due to an altered acetolactate
synthase that is not inhibited by imazamox (11).
Animal Metabolism. Metabolism studies in the rat
showed that imazamox is rapidly excreted in the urine.
There was no accumulation of imazamox or any of its
derivatives in the liver, kidney, muscle, fat, or blood (9).
Toxicity evaluation
Imazamox has shown no mutagenic or genotoxic activity in
the Ames assay, mammalian cell gene mutation assay, in vitro chromosome aberration assay, in vitro unscheduled DNA synthesis (URS) assay, or the in vivo dominant lethal
assay inmale rats. The acute toxicity and effects on wildlife
and soilmicroflora of imazamox are shown in Table 4. This
herbicide also has a low potential for bioaccumulation
in fish.
Check Digit Verification of cas no
The CAS Registry Mumber 114311-32-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,3,1 and 1 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 114311-32:
(8*1)+(7*1)+(6*4)+(5*3)+(4*1)+(3*1)+(2*3)+(1*2)=69
69 % 10 = 9
So 114311-32-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H19N3O4/c1-8(2)15(3)14(21)17-12(18-15)11-10(13(19)20)5-9(6-16-11)7-22-4/h5-6,8H,7H2,1-4H3,(H,19,20)(H,17,18,21)
114311-32-9Relevant articles and documents
Preparation method for imidazolinone compound
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Paragraph 0048; 0052, (2019/03/29)
The invention provides a preparation method for an imidazolinone compound, belongs to the technical field of organic synthesis, and can solve the problems that a large amount of wastewater is producedand the content of impurities in the product is high in the existing process for preparing the imidazolinone compound. According to the preparation method for the imidazolinone compound provided by the invention, a solution of 5-alkyl pyridine-2,3-phthalate is synthesized from ammonium carbonate; the steps of adding water, extracting, refining and the like are avoided in post-treatment; the obtained solution of the 5-alkyl pyridine-2,3-phthalate is used for subsequent reaction; and the wastewater is not produced. Then, a catalyst is added in the process of preparing 5-alkyl pyridine-2,3-dimethylbenzene anhydride, and the pH is controlled in the subsequent reaction process, so that the production of the impurities can be avoided, and the product purity is improved. The imidazolinone compound prepared by the method provided by the invention can be used as a high-efficiency herbicide.
PROCESS FOR MANUFACTURING 5-CHLOROMETHYL-2,3-PYRIDINE DICARBOXYLIC ACID ANHYDRIDES
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Page/Page column 17, (2010/06/15)
A process for manufacturing 5-chloromethyl-2,3-pyridine dicarboxylic acid anhydrides (I) wherein Z is hydrogen or halogen; Z1 is hydrogen, halogen, cyano or nitro; comprising the steps of (i) reacting a compound of formula (II), wherein the symbols have the meaning given in formula (I), with a chlorinating agent, optionally in the presence of a radical initiator in a solvent selected from halogenated hydrocarbons, and (ii) crystallizing the compound (I) formed in step (i) from a solvent selected from chlorobenzene, 1,2-dichlorobenzene, 1,3-dichlorobenzene, 1,4-dichlorobenzene, dichloroethane, trichloromethane, dichloromethane, toluene, xylenes, ethyl acetate, methyl tert.-butyl ether, and mixtures thereof. Compounds (I) are useful intermediates in the synthesis of herbicidal imidazolinones.
Method for safening herbicides in cereal crops using 5-aryloxy-1,2-(disubstituted)benzene compounds
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, (2008/06/13)
There is provided a method for safening herbicides in cereal crop plants by using 5-aryloxy-1,2 -(disubstituted)benzene compounds of formula I STR1 Further provided are compositions comprising a 5-aryloxy-1,2-(disubstituted)benzene compound of formula I.
