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3-azidopropyl 3,4,6-tri-O-acetyl-2-(2,2,2-trichloroethoxycarbonylamino)-2-deoxy-β-D-galactopyranosyl-(1->3)-2,4,6-tri-O-benzyl-β-D-galactopyranosyl-(1->4)-2,3,6-tri-O-benzyl-β-D-galactopyranosyl-(1->4)-2,4,6-tri-O-benzyl-β-D-glucopyranosyside is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1143374-07-5

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1143374-07-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1143374-07-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,3,3,7 and 4 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1143374-07:
(9*1)+(8*1)+(7*4)+(6*3)+(5*3)+(4*7)+(3*4)+(2*0)+(1*7)=125
125 % 10 = 5
So 1143374-07-5 is a valid CAS Registry Number.

1143374-07-5Downstream Products

1143374-07-5Relevant academic research and scientific papers

Chemoenzymatic syntheses of tumor-associated carbohydrate antigen globo-H and stage-specific embryonic antigen 4

Wang, Zhen,Gilbert, Michel,Eguchi, Hironobu,Yu, Hai,Cheng, Jiansong,Muthana, Saddam,Zhou, Luyuan,Wang, Peng George,Chen, Xi,Huang, Xuefei

supporting information; experimental part, p. 1717 - 1728 (2009/11/30)

Gangliosides have attracted much attention due to their important biological properties. Herein we report the first chemoenzymatic syntheses oftwo globo series of ganglioside oligosaccharides, Globo-H 1 and stage-specific embryonic antigen-4 (SSEA-4) 2. The common precursor SSEA-3 pentasaccharide for these two compounds was assembled rapidly using the pre-activation-based one-pot glycosylation method. The stereoselectivity in forming the 1,2-cis linkage in SSEA-3 was attributed to a steric buttressing effect of the donor rather than electronic properties ofthe glycosyl donors. SSEA-3 was then successfully fucosylated by the fucosyltransferase WbsJ and sialylated by sialyltransferases CST-I and PmST1 producing Globo-H and SSEA-4, respectively.

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