646058-15-3Relevant academic research and scientific papers
Carbohydrate-lipid constructs and their use in preventing or treating viral infection
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Page/Page column 25, (2016/01/30)
The invention relates to selected carbohydrate-lipid constructs and their use as mimics of ligands for receptors expressed by virus. In particular, the invention relates to the use of selected carbohydrate-lipid constructs in methods of inhibiting virus infection and/or promoting clearance of virus from infected subjects. Carbohydrate-lipid constructs selected for use in these methods where the virus is Human Immunodeficiency Virus (HIV) are provided.
An efficient approach for total synthesis of aminopropyl functionalized ganglioside GM1b
Sun, Bin,Jiang, Heyan
, p. 5711 - 5715 (2012/11/13)
A highly efficient protocol for the synthesis of aminopropyl functionalized ganglioside GM1b has been described. The full protected ganglioside GM1b was obtained in 71% yield within 5 h. The key feature of the synthetic approach was the use of sialic acid
Multi-component one-pot synthesis of the tumor-associated carbohydrate antigen globo-H based on preactivation of thioglycosyl donors
Wang, Zhen,Zhou, Luyuan,El-Boubbou, Kheireddine,Ye, Xin-Shan,Huang, Xuefei
, p. 6409 - 6420 (2008/02/10)
(Chemical Equation Presented) Two efficient routes for the rapid assembly of the tumor-associated carbohydrate antigen Globo-H hexasaccharide 2 by a preactivation based iterative one-pot strategy are reported. The first method involves the sequential coup
Synthesis of cancer-associated glycoantigens: stage-specific embryonic antigen 3 (SSEA-3)
Pornsuriyasak, Papapida,Demchenko, Alexei V.
, p. 1458 - 1466 (2007/10/03)
The synthesis of the tumor-associated carbohydrate antigens SSEA-3 and Gb3 in a semi-convergent fashion using building blocks bearing a S-thiazolinyl (STaz) moiety is reported. Complete stereoselective control of a difficult α-(1→4)-galactosylation and hi
