114346-67-7

Upstream product

• 62918-41-6 (E)-3-(4-Chloro-phenyl)-1-naphthalen-2-yl-propenone 
• 100-63-0 phenylhydrazine 
• 59-88-1 phenylhydrazine hydrochloride 
• 93-08-3 methyl 2-naphthyl ketone 
• 104-88-1 4-chlorobenzaldehyde 
• 62918-41-6 (2E)-3-(4-chlorophenyl)-1-naphthalen-2-yl-prop-2-en-1-one 

Relevant academic research and scientific papers

Synthesis of 1-substituted 3,5-diaryl-2-pyrazolines by the reaction of α,β-unsaturated ketones with hydrazines

1-Acetyl-, 1-propionyl- and 1-phenyl-3,5-diaryl-2-pyrazolines have been synthesized by the reaction of the appropriate α,β-unsaturated ketones with hydrazine or phenylhydrazine in hot acetic acid or propionic acid. Structures of all new 2-pyrazolines 16-4

Synthesis, spectral studies and antimicrobial activities of some 2-naphthyl pyrazoline derivatives

A series of 2-naphthyl pyrazolines were synthesized by the cyclization of 2-naphthyl chalcones and phenylhydrazine hydrochloride in the presence of sodium acetate. The yields of pyrazoline derivatives are more than 80%. The synthesized pyrazolines were characterized by their physical constants, IR, 1H, 13C and MS spectra. From the IR and NMR spectra the CN (cm-1) stretches, the pyrazoline ring proton chemical shifts (ppm) of δHa, Hb and Hc and also the carbon chemical shifts (ppm) of δCN are correlated with Hammett substituent constants, F and R, and Swain-Lupton's parameters using single and multi-regression analyses. From the results of linear regression analysis, the effect of substituents on the group frequencies has been predicted. The antimicrobial activities of all synthesized pyrazolines have been studied.

Silica-supported synthesis of some 1,3,5-trisubstituted 2-pyrazolines under solvent-free and microwave irradiation conditions

A simple method for the synthesis of 2-pyrazolines is described which occurs on silica surface under solvent-free conditions within 110-180 sec using microwave irradiation. The results obtained indicate that the use of silica gel as a support in pyrazolin

Microwave-assisted synthesis of some 3,5-arylated 2-pyrazolines

Condensation of 2-acetylnaphthalene with benzaldehydes under microwave irradiation affords chalcones which undergo facile and clean cyclizations with hydrazines RNHNH2 (R= H, Ph, Ac) to afford 3,5-arylated 2-pyrazolines in quantitative yields,