1144040-47-0

Upstream product

• 846036-36-0 N-[6-(4-benzyloxy-butoxy)-3-formyl-pyridin-2-yl]-2,2-dimethyl-propionamide 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 4541-14-4 4-benzyloxy-butan-1-ol 
• 127446-34-8 N-(6-chloro-3-formylpyridin-2-yl)-2,2-dimethylpropionamide 

Relevant academic research and scientific papers

PROCESS FOR MAKING A TETRAHYDRO-PYRIDOAZEPIN-8-ONE COMPOUND

The present invention relates to a method of preparing 2-{4-[4-(7-fluoro-naphthalen-l- yl)-piperazin- 1 -yl]-butoxy } -5,6,7,9-tetrahydro- 1 ,7,9-triaza-benzocyclohepten-8-one. The method comprises reacting l-(7-fluoro-naphthalen-l-yl)-piperazine hydrochloride with a compound of formula (II) wherein L in formula (II) is a leaving group.

TETRAHYDRO-PYRIDOAZEPIN-8-ONES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA

Compounds of formula 1 are disclosed, wherein G, D, A, Q, Y, Z, and R1 through R10 are defined in the specification. Also provided are descriptions of processes for preparing compounds of formula 1, intermediates used in making the same, and pharmaceutical compositions containing such compounds and their use in the treatment of central nervous system disorders and other disorders.