1144041-02-0Relevant articles and documents
Discovery of μ-opioid selective ligands derived from 1-aminotetralin scaffolds made via metal-catalyzed ring-opening reactions
Dockendorff, Chris,Jin, Shujuan,Olsen, Madeline,Lautens, Mark,Coupal, Martin,Hodzic, Lejla,Spear, Nathan,Payza, Kemal,Walpole, Christopher,Tomaszewski, Miroslaw J.
, p. 1228 - 1232 (2009)
A series of 1-aminotetralin scaffolds was synthesized via metal-catalyzed ring-opening reactions of heterobicyclic alkenes. Small libraries of amides and amines were made using the amino group of each scaffold as a handle. Screening of these libraries aga