1144043-02-6Relevant articles and documents
A copper-catalyzed, pH-neutral construction of high-enantiopurity peptidyl ketones from peptidic S-acylthiosalicylamides in air at room temperature
Liebeskind, Lanny S.,Yang, Hao,Li, Hao
supporting information; experimental part, p. 1417 - 1421 (2009/07/18)
A copper-catalyzed transformation of peptidic thiol esters and boronic acids gives peptidyl ketones and takes place in DMF or DMF/H2O at room temperature in air (see scheme). This aerobic reaction only occurs at a thiol ester group capable of coordinating