1144080-29-4 Usage
Explanation
The molecular formula representing the number of carbon (C), hydrogen (H), nitrogen (N), and oxygen (O) atoms in the compound.
Explanation
Belonging to a class of chemical compounds primarily composed of carbon and hydrogen atoms.
Explanation
Contains a nitrogen-nitrogen bond (R2N-NR2) and is derived from hydrazine (NH2-NH2).
4. Bicyclic spiro ring system
Explanation
A unique structure consisting of two rings (one six-membered oxygen-containing ring and one five-membered carbon ring) connected in a spiro manner.
Explanation
The hydrazine functional group is attached to the eighth carbon atom in the compound.
Explanation
Used in the development of new drugs and advanced materials due to its versatile chemical properties.
Explanation
The compound's unique structure and properties make it a candidate for further research and development in various fields, including medicine and material science.
Type of compound
Organic compound
Functional group
Hydrazine derivative
Attachment point
Eight-carbon atom
Applications
Organic synthesis and pharmaceuticals
Potential uses
Development of new drugs and advanced materials
Check Digit Verification of cas no
The CAS Registry Mumber 1144080-29-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,4,0,8 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1144080-29:
(9*1)+(8*1)+(7*4)+(6*4)+(5*0)+(4*8)+(3*0)+(2*2)+(1*9)=114
114 % 10 = 4
So 1144080-29-4 is a valid CAS Registry Number.
1144080-29-4Relevant academic research and scientific papers
HETEROCYCLE SUBSTITUTED AMINO-PYRIDINE COMPOUNDS AND METHODS OF USE THEREOF
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Paragraph 0374; 0376, (2016/04/20)
The present disclosure relates to heterocycle substituted amino-pyridine compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
Pyrazolopyrimidines as highly potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): Optimization of the 1-substituent
Curran, Kevin J.,Verheijen, Jeroen C.,Kaplan, Joshua,Richard, David J.,Toral-Barza, Lourdes,Hollander, Irwin,Lucas, Judy,Ayral-Kaloustian, Semiramis,Yu, Ker,Zask, Arie
scheme or table, p. 1440 - 1444 (2010/07/06)
A series of pyrazolopyrimidine mammalian Target Of Rapamycin (mTOR) inhibitors with various substituents at the 1-position have been prepared, resulting in compounds with excellent potency, selectivity and microsomal stability. Combination of a 1-cyclohexyl ketal group with a 2,6-ethylene bridged morpholine in the 4-position and a ureidophenyl group in the 6-positon resulted in compound 8a, that selectively suppressed key mTOR biomarkers in vivo for at least 8 h following iv administration and showed excellent oral activity in a xenograft tumor model.
