114414-60-7Relevant articles and documents
A universal strategy for preparing protected C-terminal peptides on the solid phase through an intramolecular click chemistry-based handle
Gongora-Benitez, Miriam,Cristau, Michele,Giraud, Matthieu,Tulla-Puche, Judit,Albericio, Fernando
supporting information; experimental part, p. 2313 - 2315 (2012/05/04)
A new universal strategy exploits DKP formation in a dipeptide moiety whose C-terminal residue is blocked by a leaving group. It enables both synthesis of C-terminal protected peptides that are useful for convergent synthesis of large peptides and use of a C-terminal permanent protecting group that can be cleaved by catalytic hydrogenation to release the peptide. The Royal Society of Chemistry.