1144503-23-0Relevant academic research and scientific papers
Synthetic method for preparing marine alkaloid Bacuacuacuanin-L intermediate
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Paragraph 0078; 0083, (2020/07/13)
The invention discloses a synthesis method for preparing a marine alkaloid Baculiferin-L intermediate. According to the method, a novel synthesis route suitable for the Baculiferin-L intermediate is designed, which is started from a raw material, substitu
A general method for the synthesis of N-unsubstituted 3,4-diarylpyrrole-2, 5-dicarboxylates
Fukuda, Tsutomu,Hayashida, Yukie,Iwao, Masatomo
experimental part, p. 1105 - 1122 (2010/09/16)
A general method for the synthesis of N-unsubstituted 3,4-diarylpyrrole-2, 5-dicarboxylates (3) has been developed. The key reactions involved are the Hinsberg-type synthesis of dimethyl N-benzyl-3,4-dihydroxypyrrole-2,5- dicarboxylate (6) followed by palladium-catalyzed Suzuki-Miyaura coupling of its bis-triflate derivative (7). The N-benzyl protecting group of the resulting 3,4-diaryl pyrrole-2,5-dicarboxyl ates (8) is cleanly removed under hydrogenolytic or solvolytic conditions.
