114457-87-3

Basic information

• Product Name: (2S,3R)-2-<(tert-butyloxycarbonyl)amino>-1-cyclohexyl-3-hydroxy-6-methylheptan-4-one
• Synonyms: (2S,3R)-2-<(tert-butyloxycarbonyl)amino>-1-cyclohexyl-3-hydroxy-6-methylheptan-4-one
• CAS NO: 114457-87-3
• Molecular Weight: 341.491
• Mol File: 114457-87-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,3R)-2-<(tert-butyloxycarbonyl)amino>-1-cyclohexyl-3-hydroxy-6-methylheptan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-2-<(tert-butyloxycarbonyl)amino>-1-cyclohexyl-3-hydroxy-6-methylheptan-4-one(114457-87-3)
• EPA Substance Registry System: (2S,3R)-2-<(tert-butyloxycarbonyl)amino>-1-cyclohexyl-3-hydroxy-6-methylheptan-4-one(114457-87-3)

Safety Data

• Hazardous Substances Data: 114457-87-3(Hazardous Substances Data)

Upstream product

• 5674-02-2 2-methylpropylmagnesium chloride 
• 117499-02-2 ((S)-2-Cyano-1-cyclohexylmethyl-2-trimethylsilanyloxy-ethyl)-carbamic acid tert-butyl ester 
• 1046536-21-3 3-<(tert-butyloxycarbonyl)amino>-4-cyclohexyl-2-hydroxybutyronitrile 
• 98105-42-1 (S)-2-(t-butoxycarbonylamino)-3-cyclohexyl-1-propanal 
• 103322-56-1 tert-butyl [(1S)-2-cyclohexyl-1-(hydroxymethyl)ethyl]carbamate 

Downstream Products

• 104882-10-2 (2S,3R,4S)-2-[(tert-butyloxycarbonyl)amino]-1-cyclohexyl-3,4-dihydroxy-6-methylheptane 

Relevant articles and documents

Enantioselective synthesis of the (syn,anti)-1-amino-2,3-diol subunit of renin inhibition by reaction of β-lactams with a Grignard reagent

A new approach to the BOC-protected amino diol 1a via the opening of 3,4-cis-disubstituted β-lactam 3 with isobutylmagnesium chloride is described. Nonracemic β-lactam 3 could be obtained by enzymatic resolution of the 3-acetoxy-β-lactam 4 or from a chira