114469-39-5

Basic information

• Product Name: (2S,4S,5S)-5-benzyloxycarbonylamino-6-cyclohexyl-4-hydroxy-2-isopropyl hexanolide
• Synonyms: (2S,4S,5S)-5-benzyloxycarbonylamino-6-cyclohexyl-4-hydroxy-2-isopropyl hexanolide
• CAS NO: 114469-39-5
• Molecular Weight: 387.519
• Mol File: 114469-39-5.mol

Chemical Properties

• CAS DataBase Reference: (2S,4S,5S)-5-benzyloxycarbonylamino-6-cyclohexyl-4-hydroxy-2-isopropyl hexanolide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S,5S)-5-benzyloxycarbonylamino-6-cyclohexyl-4-hydroxy-2-isopropyl hexanolide(114469-39-5)
• EPA Substance Registry System: (2S,4S,5S)-5-benzyloxycarbonylamino-6-cyclohexyl-4-hydroxy-2-isopropyl hexanolide(114469-39-5)

Safety Data

• Hazardous Substances Data: 114469-39-5(Hazardous Substances Data)

Upstream product

• 118041-20-6 <3S-<3α,5β(R^*)>>-5-(2-Cyclohexyl-1-azidoethyl)dihydro-3-isopropyl-2(3H)-furanone 
• 501-53-1 benzyl chloroformate 
• 114469-37-3 ((1S,2R)-1-Cyclohexylmethyl-2-hydroxy-3-iodo-propyl)-carbamic acid benzyl ester 
• 114469-35-1 3-<(benzyloxycarbonyl)amino>-4-cyclohexyl-1-iodo-2-<(trimethylsilyl)oxy>-(2R,3S)-butane 
• 105852-50-4 3-(benzyloxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyl-5-(iodomethyl)-(4S,5R)-1,3-oxazolidine 
• 556-24-1 methyl 3-methylbutanoate 
• 105852-42-4 2-<<3-(benzyloxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyl-(4S)-1,3-oxazolidin-5-yl>methyl>-3-methyl-(2S)-butyric acid 
• 142688-82-2 (2S,3S,5S)-2-benzyloxycarbonylamino-1-cyclohexyl-5-isopropylhexane-3,6-diol 

Downstream Products

• 142688-82-2 (2S,3S,5S)-2-benzyloxycarbonylamino-1-cyclohexyl-5-isopropylhexane-3,6-diol 
• 114469-40-8 (2R,4S,5S)-5-benzyloxycarbonylamino-6-cyclohexyl-4-hydroxy-2-isopropyl hexanolide 

Relevant articles and documents

Dipeptide Isosteres. 2. Synthesis of Hydroxyethylene Dipeptide Isostere Diastereomers From a Common γ-Lactone Intermediate. Preparation of Renin and HIV-1 Protease Inhibitor Transition State Mimics.

A general strategy for the synthesis of the hydroxyethylene dipeptide isostere diastereomers C or D has been developed.The syntheses proceeded through a common γ-lactone intermediate A or B.The C(3α)γ-lactone diastereomer A was prepared from the N-Cbz pro

Processes for the preparation of 5-amino-4-hydroxyvaleric acid derivatives

The invention relates to novel processes and intermediates for the preparation of 5-amino-4-hydroxyvaleric acid derivatives of the formula STR1 in which R1 represents hydrogen, optionally substituted alkyl, cycloalkyl, cycloalkyl-lower alkyl, a

Synthesis and biological activity of some transition-state inhibitors of human renin

A series of renin inhibitors containing the dipeptide transition state mimics (2S,4S,5S)-5-amino-4-hydroxy-2-isopropyl-7-methyloctanoic acid (Leu-(OH)-Val) and (2S,4S,5S)-5-amino-4-hydroxy-2-isopropyl-6-cyclohexylhexanoic acid (Cha-(OH)-Val) was prepared.