114486-16-7

Upstream product

• 136918-14-4 phthalimide 
• 99891-37-9 (-)-(2S,3S)-4-benzyloxy-2,3-bis(methoxymethoxy)butane-1-ol 
• 99891-37-9 (2S,3R)-4-Benzyloxy-2,3-bis-methoxymethoxy-butan-1-ol 
• 99891-36-8 2,3-Bis-methoxymethoxy-butane-1,4-diol 
• 100449-52-3 2,3-Bis-methoxymethoxy-succinic acid diethyl ester 
• 100449-52-3 (+)-(2R,3R)-diethyl 2,3-bismethoxymethoxybutanedioate 
• 99891-36-8 (-)-(2S,3S)-2,3-bis(methoxymethoxy)butane-1,4-diol 

Downstream Products

• 98207-76-2 (-)-(2S,3S) ethyl 1-amino-4-benzyloxy-2,3-bis(methoxymethoxy)butane-N-carboxylate 
• 98207-76-2 ((2S,3R)-4-Benzyloxy-2,3-bis-methoxymethoxy-butyl)-carbamic acid ethyl ester 
• 114495-16-8 ((3S,4S)-1-Benzoyl-3,4-bis-methoxymethoxy-pyrrolidin-2-yl)-acetic acid ethyl ester 
• 114486-22-5 ((2S,3S,4S)-1-Benzoyl-3,4-dihydroxy-pyrrolidin-2-yl)-acetic acid ethyl ester 
• 114495-13-5 ((3R,4S)-2-Hydroxy-3,4-bis-methoxymethoxy-pyrrolidin-1-yl)-phenyl-methanone 
• 114486-19-0 (-)-(2S,3S)-N-benzoyl-4-hydroxy-2,3-bis(methoxymethoxy)butylamine 
• 114515-66-1 (3aR,6S)-4-Benzoyl-6-hydroxy-hexahydro-furo[3,2-b]pyrrol-2-one 
• 114486-17-8 (-)-(2S,3S)-N-benzoyl-4-benzyloxy-2,3-dimethoxymethoxybutylamine 

Relevant academic research and scientific papers

1,2-Asymmetric Induction in Intramolecular Michael Reaction. A Novel and Enantioselective Route to (+)-Geissman Lactone

The Horner-Emmons reaction of the hemiacetal (19), derived from L-(+)-diethyl tartrate, was found to give the pyrrolidine (21) via an intramolecular Michael reaction as a mixture of diastereoisomers which, after treatment with ethanethiol and boron triflu

A CHIRAL ROUTE TO PYRROLIZIDINE ALKALOIDS VIA INTRAMOLECULAR MICHAEL REACTION

Wittig-Horner reaction of 10 gave the pyrrole (11) as a diastereomeric mixture via the intramolecular Michael reaction, one of the diastereomers could be converted to the Geissman lactone (4), a synthon for some pyrrolizidine alkaloids.