98207-76-2Relevant academic research and scientific papers
1,2-Asymmetric Induction in Intramolecular Michael Reaction. A Novel and Enantioselective Route to (+)-Geissman Lactone
Shishido, Kozo,Sukegawa, Yuko,Fukumoto, Keiichiro
, p. 993 - 1004 (2007/10/02)
The Horner-Emmons reaction of the hemiacetal (19), derived from L-(+)-diethyl tartrate, was found to give the pyrrolidine (21) via an intramolecular Michael reaction as a mixture of diastereoisomers which, after treatment with ethanethiol and boron triflu
A CHIRAL ROUTE TO PYRROLIZIDINE ALKALOIDS VIA INTRAMOLECULAR MICHAEL REACTION
Shishido, Kozo,Sukegawa, Yuko,Fukumoto, Keiichiro,Kametani, Tetsuji
, p. 1629 - 1633 (2007/10/02)
Wittig-Horner reaction of 10 gave the pyrrole (11) as a diastereomeric mixture via the intramolecular Michael reaction, one of the diastereomers could be converted to the Geissman lactone (4), a synthon for some pyrrolizidine alkaloids.
