1145-50-2

Upstream product

• 93578-34-8 2-[1-(3-Methoxy-phenyl)-meth-(E)-ylidene]-succinic acid diethyl ester 
• 591-31-1 3-methoxy-benzaldehyde 
• 106-65-0 Dimethyl succinate 

Downstream Products

• 80459-44-5 dimethyl (E)-2-(3-methoxybenzylidene)succinate 
• 338945-89-4 (2R)-2-(3-methoxybenzyl)succinic acid 
• 20940-75-4 2-(3-methoxybenzyl)succinic acid 
• 24833-31-6 1,2,3,4-tetrahydro-7-methoxy-2-naphthalenecarboxylic acid 

Relevant academic research and scientific papers

The practical synthesis of (2S)-7-methoxy-1,2,3,4-tetrahydro-2-naphthylamine via optical resolution of 2-(3-methoxybenzyl)succinic acid

We describe the practical synthetic route for (2S)-7-methoxy-1,2,3,4-tetrahydro-2-naphthylamine [(2S)-2-amino-7-methoxytetraline; (S)-AMT]. (2R)-2-(3-Methoxybenzyl)succinic acid [(R)-1] was obtained by the optical resolution of 2-(3-methoxybenzyl)succinic

NOVEL BUTADIENE DERIVATIVES, PROCESS FOR PREPARATION OF THE SAME AND INTERMEDIATES FOR THE SYNTHESIS THEREOF

A butadiene derivative having an excellent inhibitory activity on the PAI-1, which is represented by the general formula [I]: wherein R1 is a hydrogen atom or a lower alkyl group, R2 is a lower alkyl group, R3 is a lower alkoxy group, R4 is a hydrogen atom or a lower alkyl group, R5 is a lower alkyl group, or a pharmaceutically acceptable salt thereof, a process a process for preparing the same and an intermediate thereof.