114564-97-5

Upstream product

• 98-88-4 benzoyl chloride 
• 6212-33-5 2-(4-Chlorophenyl)glycine 

Downstream Products

• 136603-04-8 4,4'-Bis-<2-phenyl-4-p-chlorophenyl-2-oxazolin-5-one> 
• 114581-53-2 [4-(4-Chloro-phenyl)-2-phenyl-oxazol-5-yl]-acetic acid ethyl ester 
• 114564-80-6 4-Benzoylamino-4-(4-chloro-phenyl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-butyric acid ethyl ester 
• 1208868-00-1 C₃₆H₂₆ClNO₃ 

Relevant academic research and scientific papers

Enantioselective iridium catalyzed α-alkylation of azlactones by a tandem asymmetric allylic alkylation/aza-Cope rearrangement

The development of an iridium catalyzed enantioselective α-alkylation of azlactones has been described. The reaction provides rapid access to a wide range of enantio-enriched quaternary carbon center allylated 2,4-diaryloxazol-5(2H)-ones in excellent yiel

Catalyst-free synthesis of N -(1,7-dioxotetrahydropyrazolo[1,2-a]pyrazol-2- yl)benzamide derivatives by 1,3-dipolar cycloaddition and rearrangement

N-(1,7-Dioxotetrahydropyrazolo[1,2-a]pyrazol-2-yl)-benzamide derivatives, a novel class of compounds, were synthesized by 1,3-dipolar cycloaddition of azomethine imines with azlactones and subsequent rearrangement. The reaction can be completed rapidly under mild conditions without a catalyst. Georg Thieme Verlag Stuttgart New York.

5-Oxazolones, IV Reactions of 5(4H)-Oxazolones with Triphenylphosphonium Methylides

The Wittig reaction of ethyl (triphenylphosphoranylidene)acetate (2a) with the carbonyl group of trisubstituted 5(4H)-oxazolones 1a-c afforded ethyl 5(4H)-oxazolylideneacetates 3a-c and triphenylphosphane oxide.Starting from oxazolones 1d-i and ylide 2a, methyleneoxazoles 3d, e and ethyl 5-oxazoleacetates 4a-f were obtained besides ylides 5a-e deriving from the nucleophilic attack of the ylide at 1 and subsequent opening of the oxazole ring.Oxazolones 1a-c reacted also with triphenylphosphonium phenylmethylide (2b) to yield methyleneoxazoles 3f,g and ylides 5f-h.By treating triphenylphosphonium methylide (2c) and -methoxymethylide (2d) with 1a-c only open-chain compounds 5i-k and 5l-n, respectively, were obtained.