1146080-41-2Relevant academic research and scientific papers
InCl3 mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis
Sunke, Rajnikanth,Bankala, Ramudu,Thirupataiah,Ramarao, E.V.V. Shivaji,Kumar, Jetta Sandeep,Doss, Hari Maduri,Medishetti, Raghavender,Kulkarni, Pushkar,Kapavarapu, Ravi Kumar,Rasool, Mahaboobkhan,Mudgal, Jayesh,Mathew, Jessy E.,Shenoy, Gautham G.,Parsa, Kishore V.L.,Pal, Manojit
, p. 198 - 215 (2019)
A new class of PDE4 inhibitors were designed and synthesized via the InCl3 mediated heteroarylation of indoles and their further derivatization through the Pd(II)-catalyzed C[sbnd]H activation strategy. This effort allowed us to discover a seri
Metal catalyst free cyclization of 3-alkynyl substituted 2-(indol-3-yl)quinoxalines in TFA alone: a new synthesis of indolophenazines
Kumar, K. Shiva,Bhaskar, Boyapally,Ramulu, Meesa Siddi,Kumar, N. Praveen,Ashfaq, Mohd Ashraf,Pal, Manojit
supporting information, p. 82 - 87 (2016/12/27)
TFA alone was found to be remarkably effective for the intramolecular hydroarylation (IMHA) of alkynes when employed as a solvent in the cyclization of 3-alkynyl substituted 2-(indol-3-yl)quinoxalines. This simple and metal free cyclization method afforde
AlCl3 induced (hetero)arylation of 2,3-dichloroquinoxaline: A one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents
Kumar, K. Shiva,Rambabu,Sandra, Sandhya,Kapavarapu, Ravikumar,Krishna, G. Rama,Basaveswara Rao,Chatti, Kiranam,Reddy, C. Malla,Misra, Parimal,Pal, Manojit
experimental part, p. 1711 - 1722 (2012/04/11)
A direct and single-step method has been developed for the synthesis of mono and 2,3-disubstituted quinoxalines by using a AlCl3 induced (hetero)arylation of 2,3-dichloroquinoxaline. Both symmetrical and unsymmetrical 2,3-disubstituted quinoxal
