114614-81-2Relevant academic research and scientific papers
Chiral Vinyl Anions for "Carbonyl Umpolung". Highly Stereoselective Addition of a Novel Enantiomerically Pure Vinyllithium Reagent to Aldehydes
Mahler, Hellmut,Braun, Manfred
, p. 1379 - 1395 (2007/10/02)
The vinyllithium reagent 13 and its enantiomer are generated by a bromine/lithium exchange reaction starting from dibromoalkenes 11 and 12, both available from the corresponding enantiomer of ethyl lactate.When 13 is allowed to react with aldehydes or wit
STEREOSELECTIVE ADDITION OF A NOVEL, ENANTIOMERICALLY PURE VINYLLITHIUM REAGENT TO PROCHIRAL CARBONYL COMPOUNDS
Mahler, Hellmut,Braun, Manfred
, p. 5145 - 5148 (2007/10/02)
The vinyllithium reagent (S)-3, generated from the alkene 6 by bromine/lithium exchange, reacts stereoselectively with prochiral carbonyl compounds.Debromination of the adducts 4/8 affords the (Z)-olefins 11/12, which can be cleaved by ozonolyzis.
