1146213-79-7

Basic information

• Product Name: 1-(2-(4-(4-fluorobenzyl)piperazin-1-carbonyl)-1H-indol-3-yl)ethanone
• Synonyms: 1-(2-(4-(4-fluorobenzyl)piperazin-1-carbonyl)-1H-indol-3-yl)ethanone
• CAS NO: 1146213-79-7
• Molecular Weight: 379.434
• Mol File: 1146213-79-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-(4-(4-fluorobenzyl)piperazin-1-carbonyl)-1H-indol-3-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(4-(4-fluorobenzyl)piperazin-1-carbonyl)-1H-indol-3-yl)ethanone(1146213-79-7)
• EPA Substance Registry System: 1-(2-(4-(4-fluorobenzyl)piperazin-1-carbonyl)-1H-indol-3-yl)ethanone(1146213-79-7)

Safety Data

• Hazardous Substances Data: 1146213-79-7(Hazardous Substances Data)

Upstream product

• 117140-77-9 1H-indole-2,5-dicarboxylic acid 
• 70931-28-1 1-(4-fluorophenylmethyl)piperazine 

Relevant articles and documents

Investigations of SCIO-469-like compounds for the inhibition of p38 MAP kinase

The p38 MAP kinase is implicated in the release of the pro-inflammatory cytokines TNFα and IL-1b. Inhibition of cytokine release may be a useful treatment for inflammatory conditions such as rheumatoid arthritis and Crohn's disease. A new lead structure for p38 MAP kinase inhibition was identified. Herein, we report the SAR of this new class of p38 inhibitors.