1146221-86-4 Usage
Structure
Pyrrolopyridine derivative with a carbonitrile group attached to the 3-position of the pyrrolopyridine ring
Substituents
A tert-butyl group at the 1-position and a trifluoromethyl group at the 4-position
Potential applications
Pharmaceutical research and development, particularly in the discovery of new drugs for various therapeutic indications
Value
Unique structure and chemical properties make it a potentially valuable building block for the synthesis of novel drug candidates with enhanced pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1146221-86-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,6,2,2 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1146221-86:
(9*1)+(8*1)+(7*4)+(6*6)+(5*2)+(4*2)+(3*1)+(2*8)+(1*6)=124
124 % 10 = 4
So 1146221-86-4 is a valid CAS Registry Number.
1146221-86-4Relevant academic research and scientific papers
Facile synthesis of fluorinated pyrrolo[2,3-b]pyridines
Groth, Ulrich,Iaroshenko, Viktor O.,Wang, Yan,Wesch, Thomas
experimental part, p. 456 - 460 (2009/08/09)
With the purpose to synthesize novel ADAs (adenosine deaminase) and IMPDH (inosine 5′-monophosphate dehydrogenase) inhibitors the reaction of 5-amino-1-tert-butyl-1H-pyrrolo-3-carbonitrile with fluorinated 1,3-biselectrophiles was studied. An efficient an
Synthesis of fluorinated pyrrolo[2,3-b]pyridine and pyrrolo[2,3-d] pyrimidine nucleosides
Iaroshenko, Viktor O.,Wang, Yan,Sevenard, Dmitri V.,Volochnyuk, Dmitriy M.
experimental part, p. 1851 - 1857 (2010/01/16)
With the purpose of synthesizing novel ADAs (adenosine deaminase) and IMPDH (inosine 5′-monophosphate dehydrogenase) inhibitors the reactions of 5-amino-1-tert-butyl-1-H-pyrrole-3-carbonitrile with fluorinated 1,3 - bielectrophiles were studied. An effici
