114653-06-4Relevant articles and documents
SOFT BETA-ADRENERGIC BOLCKING AGENTS
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, (2008/06/13)
New soft β-adrenergic blocking agents, useful in the treatment or prevention of cardiovascular disorders and in the treatment of glaucoma, have the formula STR1 wherein n is an integer from 0 to 10; R is C. sub.6-C 12 cycloalkyl-C p H 2p--, C 6-C. sub.18 polycycloalkyl-C p H 2p--, C 6-C 18 polycycloalkenyl-C. sub.p H 2p--or C 6 C 12 cycloalkenyl-C. sub.p H 2p--(wherein p is 0, 1, 2 or 3), or together with the adjacent STR2 group represents a variety of other complex ester groupings; R 1 is C 1-C 7 alkyl; and Ar is a divalent radical containing at least one aromatic nucleus. The corresponding pharmaceutically acceptable acid addition salts are also described.