114657-00-0 Usage
Chemical structure
A derivative of barbituric acid with a substituted phenyl group and a 4'-nitrobenzyl group.
Functional groups
Contains a barbituric acid core, a phenyl group, and a 4'-nitrobenzyl group.
Application
Used as a reagent for detecting and analyzing the presence of certain biological molecules.
Suitability
Particularly suitable for labeling and detecting proteins in biochemical assays due to the presence of the nitrobenzyl group.
Usage
Commonly utilized in research and laboratory settings for its specific reactivity and usefulness in detecting and quantifying certain biological molecules.
Pharmacological properties
Part of the barbituric acid family, which is known for its pharmacological properties.
Molecular weight
Approximately 414.45 g/mol (calculated from the molecular formula).
Appearance
Likely a solid, as most barbituric acid derivatives are solid at room temperature.
Solubility
Solubility information is not provided, but it may be soluble in organic solvents like DMSO or ethanol, as is common for many barbituric acid derivatives.
Check Digit Verification of cas no
The CAS Registry Mumber 114657-00-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,6,5 and 7 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 114657-00:
(8*1)+(7*1)+(6*4)+(5*6)+(4*5)+(3*7)+(2*0)+(1*0)=110
110 % 10 = 0
So 114657-00-0 is a valid CAS Registry Number.
114657-00-0Relevant academic research and scientific papers
OXIDATION OF THIOL WITH 5-ARYLIDENE-1,3-DIMETHYLBARBITURIC ACID: APPLICATION TO SYNTHESIS OF UNSYMMETRICAL DISULFIDE
Tanaka, Kiyoshi,Chen, Xing,Yoneda, Fumio
, p. 3241 - 3250 (2007/10/02)
5-Arylidene-1,3-dimethylbarbituric acid derivatives, such as 1a and 1b, effectively oxidized both alkane- and benzenethiols to disulfides under neutral condition with concomitant formation of the dihydro compounds (2a) and (2b).Thiol adduct of the dihydro compound was prepared as a stable compound and successfully applied to the synthesis of unsymmetrical disulfide under mild condition in excellent yield.Mechanistic consideration for the oxidation was also described briefly.
OXIDATION OF THIOL BY 5-ARYLIDENE 1,3-DIMETHYLBARBITURIC ACID AND ITS APPLICATION TO SYNTHESIS OF UNSYMMETRICAL DISULFIDE
Tanaka, Kiyoshi,Chen, Xing,Kimura, Teiji,Yoneda, Fumio
, p. 4173 - 4176 (2007/10/02)
Oxidation of both aromatic and aliphatic thiols by 5-arylidene 1,3-dimethylbarbituric acid was found to proceed readily to give disulfides in good yield with concomitant reduction of the oxidant to the dihydro compound.Thiol adduct of the dihydro compound was succesfully applied to the synthesis of unsymmetrical disulfide under mild conditions in an excellent yield.
