1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid

Base Information

• Chemical Name: 1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid
• CAS No.: 114657-00-0
• Molecular Formula: C₁₉H₁₇N₃O₅S
• Molecular Weight: 399.427
• Mol file: 114657-00-0.mol

Synonyms:1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid

Chemical Property of 1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid

There total 3 articles about 1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione (114656-98-3) + benzenesulfenyl chloride (931-59-9) → 1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid (114657-00-0)

Guidance literature:

In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(00)95570-9

Reference yield:

1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione (114656-98-3) → 1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid (114657-00-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / N-chlorosuccinimide / CH₂Cl₂ / Ambient temperature

2: Et₃N / CH₂Cl₂ / Ambient temperature

With N-chloro-succinimide; triethylamine; In dichloromethane;

DOI:10.1016/S0040-4039(00)95570-9

Reference yield:

thiophenol (108-98-5) + 5-chloro-1,3-dimethyl-5-(4'-nitrobenzyl)barbituric acid (114657-03-3) → 1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid (114657-00-0)

Guidance literature:

With triethylamine; In dichloromethane; Yield given; Ambient temperature;

DOI:10.1016/S0040-4039(00)95570-9

upstream raw materials:

thiophenol

5-chloro-1,3-dimethyl-5-(4'-nitrobenzyl)barbituric acid

1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione

benzenesulfenyl chloride

Downstream raw materials:

dibutyl disulfide

butyl phenyl disulfide

diphenyldisulfane

1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione