1146629-82-4 Usage
Uses
Used in Pharmaceutical Industry:
1H-Pyrazole-1-propanal, 4-bromo-b-cyclopentyl, (bR)is used as a key intermediate in the synthesis of pharmaceutical compounds due to its unique structure and functional groups. Its potential applications include the development of new drugs with improved therapeutic properties and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, 1H-Pyrazole-1-propanal, 4-bromo-b-cyclopentyl, (bR)can be utilized as a building block for the creation of novel agrochemicals, such as pesticides and herbicides. Its unique structure and functional groups may contribute to the development of more effective and environmentally friendly products.
Used in Academic Research:
1H-Pyrazole-1-propanal, 4-bromo-b-cyclopentyl, (bR)serves as a valuable compound in academic research for the exploration of new synthetic pathways and the preparation of complex organic molecules. Its unique properties and versatility make it an attractive candidate for studying various chemical reactions and mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 1146629-82-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,6,6,2 and 9 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1146629-82:
(9*1)+(8*1)+(7*4)+(6*6)+(5*6)+(4*2)+(3*9)+(2*8)+(1*2)=164
164 % 10 = 4
So 1146629-82-4 is a valid CAS Registry Number.
1146629-82-4Relevant academic research and scientific papers
Haydl, Alexander M.,Xu, Kun,Breit, Bernhard
, p. 7149 - 7153 (2015)
Abstract The rhodium-catalyzed asymmetric N-selective coupling of pyrazole derivatives with terminal allenes gives access to enantioenriched secondary and tertiary allylic pyrazoles, which can be employed for the synthesis of medicinally important targets. The reaction tolerates a large variety of functional groups and labelling experiments gave insights into the reaction mechanism. This new methodology was further applied in a highly efficient synthesis of JAK 1/2 inhibitor (R)-ruxolitinib.
PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS
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Page/Page column 71-72, (2010/08/07)
The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.
