1146629-97-1Relevant academic research and scientific papers
A new high-yield synthetic route to PET CB1 radioligands [ 11C]OMAR and its analogs
Gao, Mingzhang,Wang, Min,Zheng, Qi-Huang
, p. 3704 - 3709 (2012/07/17)
OMAR analogs reference standards and their corresponding desmethylated precursors were synthesized from substituted anilines either in 4 and 5 steps with 27-32% and 24-31% yield, or in 3 and 4 steps with 21-30% and 19-28% yield, respectively. [11/su
Analogs of JHU75528, a PET ligand for imaging of cerebral cannabinoid receptors (CB1): Development of ligands with optimized lipophilicity and binding affinity
Fan, Hong,Kotsikorou, Evangelia,Hoffman, Alexander F.,Ravert, Hayden T.,Holt, Daniel,Hurst, Dow P.,Lupica, Carl R.,Reggio, Patricia H.,Dannals, Robert F.,Horti, Andrew G.
experimental part, p. 593 - 608 (2009/09/08)
Cyano analogs of Rimonabant with high binding affinity for the cerebral cannabinoid receptor (CB1) and with optimized lipophilicity have been synthesized as potential positron emission tomography (PET) ligands. The best ligands of the series are optimal t
