114676-97-0

Basic information

• Product Name: (2R,4R)-N-Boc-2-(fluoromethyl)-4-hydroxypyrrolidine
• Synonyms: (2r,4r)-n-boc-2-(fluoromethyl)-4-hydroxypyrrolidine;(2R,4R)-tert-Butyl 2-(fluoromethyl)-4-hydroxypyrrolidine-1-carboxylate;(2R-cis)-2-(Fluoromethyl)-4-hydroxy-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester;tert-butyl 2-(fluoroMethyl)-4-hydroxypyrrolidine-1-carboxylate
• CAS NO: 114676-97-0
• Molecular Formula: C10H18FNO3
• Molecular Weight: 219.25
• Mol File: 114676-97-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 98-99 °C
• Boiling Point: 302.7 °C at 760 mmHg
• Flash Point: 136.9 °C
• Appearance: /
• Density: 1.151
• Refractive Index: 1.471
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (2R,4R)-N-Boc-2-(fluoromethyl)-4-hydroxypyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R)-N-Boc-2-(fluoromethyl)-4-hydroxypyrrolidine(114676-97-0)
• EPA Substance Registry System: (2R,4R)-N-Boc-2-(fluoromethyl)-4-hydroxypyrrolidine(114676-97-0)

Safety Data

• Hazardous Substances Data: 114676-97-0(Hazardous Substances Data)

Usage

General Description

"(2R,4R)-N-Boc-2-(fluoromethyl)-4-hydroxypyrrolidine" is a chemical compound with the molecular formula C10H18FNO3. It is a pyrrolidine derivative with a Boc-protected amine and a fluoromethyl group attached to the 2-position and a hydroxy group attached to the 4-position. (2R,4R)-N-Boc-2-(fluoromethyl)-4-hydroxypyrrolidine is commonly used as a building block in organic synthesis and medicinal chemistry. It can be used in the preparation of various pharmaceuticals and agrochemicals. Its stereochemistry and functional groups make it a versatile and valuable intermediate in the synthesis of complex organic molecules.

InChI:InChI=1/C10H18FNO3/c1-10(2,3)15-9(14)12-6-8(13)4-7(12)5-11/h7-8,13H,4-6H2,1-3H3/t7-,8-/m1/s1

Upstream product

• 114676-75-4 (2R,4R)-1-(tert-butoxycarbonyl)-2-(fluoromethyl)-4-(tetrahydropyran-2-yloxy)pyrrolidine 
• 250122-38-4 (2R,4R)-4-benzyloxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 869527-82-2 tert-butyl (2R,4R)-4-benzyloxy-2-hydroxymethylpyrrolidine-1-carboxylate 
• 2584-71-6 cis-hydroxy-D-proline 
• 114677-05-3 (2R,4R)-2-Methanesulfonyloxymethyl-4-(tetrahydro-pyran-2-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 114676-74-3 N-α-tert-butyloxycarbonyl-cis-4-(2-tetrahydropyranyloxy)-D-prolinol 
• 114676-59-4 (2R,4R)-4-hydroxy-2-methoxycarbonylpyrrolidine hydrochloride 
• 114676-69-6 (2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 114676-90-3 (2'R,4'S)-7-<4'-amino-2'-(fluoromethyl)pyrrolidinyl>-1-(2,4-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride 

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