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tert-butyl (2R,4R)-4-benzyloxy-2-hydroxymethylpyrrolidine-1-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

869527-82-2

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869527-82-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 869527-82-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,5,2 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 869527-82:
(8*8)+(7*6)+(6*9)+(5*5)+(4*2)+(3*7)+(2*8)+(1*2)=232
232 % 10 = 2
So 869527-82-2 is a valid CAS Registry Number.

869527-82-2Relevant academic research and scientific papers

INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES

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, (2021/12/28)

Provided herein are heteroaryl inhibitors of fibroblast growth factor receptor kinases, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.

Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences

Bueno, Ana B.,Agejas, Javier,Broughton, Howard,Dally, Robert,Durham, Timothy B.,Espinosa, Juan Félix,González, Rosario,Hahn, Patric J.,Marcos, Alicia,Rodríguez, Ramón,Sanz, Gema,Soriano, José F.,Timm, David,Vidal, Paloma,Yang, Hsiu-Chiung,McCarthy, James R.

, p. 9807 - 9820 (2017/12/26)

NMR conformational analysis of a hydroxyethylamine peptide isostere developed as an aspartic protease inhibitor shows that it is a flexible architecture. Cyclization to form pyrrolidines, piperidines, or morpholines results in a preorganization of the who

Structure-based design, synthesis, X-ray studies, and biological evaluation of novel HIV-1 protease inhibitors containing isophthalamide-derived P2-ligands

Ghosh, Arun K.,Takayama, Jun,Kassekert, Luke A.,Ella-Menye, Jean-Rene,Yashchuk, Sofiya,Agniswamy, Johnson,Wang, Yuan-Fang,Aoki, Manabu,Amano, Masayuki,Weber, Irene T.,Mitsuya, Hiroaki

, p. 4903 - 4909 (2015/10/28)

We describe the design, synthesis and biological evaluation of a series of novel HIV-1 protease inhibitors bearing isophthalamide derivatives as the P2-P3 ligands. We have investigated a range of acyclic and heterocyclic amides as the extended P2-P3 ligan

COMPOUNDS CONTAINING FUSED RINGS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF

-

, (2011/11/01)

The invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating Alzheimer's disease.

BACE INHIBITORS

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Page/Page column 52-53, (2008/06/13)

The present invention provides BACE inhibitors of Formula (I): methods for their use and preparation, and intermediates for their preparation.

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