1147092-75-8Relevant academic research and scientific papers
Visible light-driven direct synthesis of ketones from aldehydes via C[sbnd]H bond activation using NiCu nanoparticles adorned on carbon nano onions
Heydari, Akbar,Khorsandi, Zahra,Metkazini, S. Fatemeh Mohammadi,Varma, Rajender S.
, (2021/11/09)
An efficient, straightforward and high yield synthetic approach is described for the direct synthesis of diaryl ketones via the C[sbnd]H bond activation of aldehydes using NiCu nanoparticles adorned on carbon nano onions as an efficient heterogeneous catalyst under the irradiation of a mercury-vapor lamp (400 w) via simple workup. This C[sbnd]H bond activation reaction appears simple and convenient with a wide substrate scope in view of its excellent synthesis prowess as illustrated in the preparation of new-approved anti-Alzheimer and anti-HIV medicinal compounds under greener and mild reaction conditions; catalyst could be recycled and reused five times without any loss of catalytic activity.
Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing
Gobbi, Silvia,Hu, Qingzhong,Foschi, Giacomo,Catanzaro, Elena,Belluti, Federica,Rampa, Angela,Fimognari, Carmela,Hartmann, Rolf W.,Bisi, Alessandra
, p. 401 - 409 (2019/02/15)
The inhibition of steroidogenic cytochrome P450 enzymes has been shown to play a central role in the management of life-threatening diseases such as cancer, and indeed potent inhibitors of CYP19 (aromatase) and CYP17 (17α hydroxylase/17,20 lyase) are curr
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors
Belluti, Federica,Piazzi, Lorna,Bisi, Alessandra,Gobbi, Silvia,Bartolini, Manuela,Cavalli, Andrea,Valenti, Piero,Rampa, Angela
experimental part, p. 1341 - 1348 (2009/09/27)
Starting from a structure-based drug design, new acetylcholinesterase inhibitors were designed and synthesized as analogues of donepezil. The compounds were composed by an aromatic function and a tertiary amino moiety connected by a suitable spacer. In pa
