116412-87-4

Basic information

• Product Name: 3,4-Dimethoxy-4'-methylbenzophenone
• Synonyms: 3,4-Dimethoxy-4'-methylbenzophenone;(3,4-dimethoxyphenyl)(p-tolyl)methanone;(3,4-dimethoxyphenyl)-(4-methylphenyl)methanone
• CAS NO: 116412-87-4
• Molecular Formula: C₁₆H₁₆O₃
• Molecular Weight: 256.3
• Mol File: 116412-87-4.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3,4-Dimethoxy-4'-methylbenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dimethoxy-4'-methylbenzophenone(116412-87-4)
• EPA Substance Registry System: 3,4-Dimethoxy-4'-methylbenzophenone(116412-87-4)

Safety Data

• Hazardous Substances Data: 116412-87-4(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 122775-35-3 3,4-Dimethoxyphenylboronic acid 
• 99-94-5 p-Toluic acid 
• 91-16-7 1,2-dimethoxybenzene 
• 4131-03-7 bis(3,4-dimethoxyphenyl)methanone 
• 874-60-2 4-methyl-benzoyl chloride 
• 89980-69-8 3,4-dimethoxyphenylmagnesium bromide 
• 423177-67-7 3,4-dimethoxy-4'-methylbenzhydrol 

Downstream Products

• 383895-73-6 4,5-dimethoxy-2-(4-methylbenzoyl)-1-(4-methylphenylsulfonamido)benzene 
• 391251-83-5 (2-amino-4,5-dimethoxyphenyl)-(4-methylphenyl)methanone 
• 340696-18-6 2-(hydroxy(4-methylphenyl)methyl)-4,5-dimethoxy-1-(4-methylphenylsulfonamido)benzene 
• 340696-27-7 4-methyl-N-{4,5-dimethoxy-2-[(5-methylfuran-2-yl)(4-methylphenyl)methyl]phenyl}-benzenesulfonamide 
• 340696-33-5 4-[5,6-dimethoxy-3-(4-methylphenyl)-1-(4-methylphenylsulfonyl)-1H-2-indolyl]-2-butanone 
• 1009314-93-5 C₁₆H₁₉NO₂ 
• 1496524-40-3 isopropyl((2S)-1-(((3,4-dimethoxylphenyl)(4-methylphenyl)methyl)amino)-3-methyl-1-oxobutan-2-yl)carbamate 
• 1620077-24-8 C₁₆H₁₇NO₃ 
• 1147092-75-8 (4-(bromomethyl)phenyl)-(3,4-dimethoxyphenyl)methanone 
• 681470-02-0 (4,5-dimethoxy-2-nitrophenyl)-(4-methylphenyl)methanone 

Relevant articles and documents

Visible light-driven direct synthesis of ketones from aldehydes via C[sbnd]H bond activation using NiCu nanoparticles adorned on carbon nano onions

An efficient, straightforward and high yield synthetic approach is described for the direct synthesis of diaryl ketones via the C[sbnd]H bond activation of aldehydes using NiCu nanoparticles adorned on carbon nano onions as an efficient heterogeneous catalyst under the irradiation of a mercury-vapor lamp (400 w) via simple workup. This C[sbnd]H bond activation reaction appears simple and convenient with a wide substrate scope in view of its excellent synthesis prowess as illustrated in the preparation of new-approved anti-Alzheimer and anti-HIV medicinal compounds under greener and mild reaction conditions; catalyst could be recycled and reused five times without any loss of catalytic activity.

Design, synthesis, and fungicidal activity of novel carboxylic acid amides represented by N-benzhydryl valinamode carbamates

Carboxylic acid amide (CAA) fungicides are an important class of agricultural fungicide with oomycete activity and low toxicity toward mammalian cells. To find CAA analogues with high activity against resistant pathogens, a series of substituted N-benzhydryl valinamide carbamate derivatives were designed and synthesized by introducing substituted aromatic rings into valinamide carbamate leads. Bioassays showed that some title compounds exhibited very good in vitro fungicidal activity against Phytophthora capsici and in vivo fungicidal activities against Pseudoperonospora cubensis. Topomer CoMFA was performed to explore the structure-activity relationship on the basis of the in vitro data. The dimethoxy substituted aromatic analogue 9e was found to display higher in vitro fungicidal activity against Phytophthora capsici than iprovalicarb but lower activity than mandipropamid, and higher in vivo fungicidal activity against Pseudoperonospora cubensis than dimethomorph at a dosage of 6.25 μg mL-1. This journal is the Partner Organisations 2014.

Simple route to 3-(2-indolyl)-1-propanones via a furan recyclization reaction

A simple route to 1-R-3-(2-indolyl)-1-propanones has been elaborated based on recyclization of 2-(2-aminobenzyl)furan derivatives. Being a modification of the Reissert indole synthesis, our approach employs the furan ring as a source of carbonyl function. This approach is general and allows varying of substituents in aromatic ring as well as in 3-position of indole nucleus.