1147097-05-9Relevant academic research and scientific papers
Highly regioselective ring opening of epoxides with thiols catalyzed by SbCl3 under solvent-free conditions
Ghazanfari, Dadkhoda,Hashemi, Mohammed M.,Akhgar, Mohammad Reza,Foroughi, Mohammad Mehdi,Najafi-Zadeh, Fariba
, p. 3018 - 3022 (2008)
The ring-opening reaction of epoxides with thiols by SbCl3 supported on Kieselguhr under solvent-free conditions, afforded high yields of β-hydroxy sulfides. Nucleophilic attack of the thiols occurs regioselectively at the less hindered side of the epoxid
Addition of unactivated thiols to epoxides and oxetanes catalyzed by a rhenium-oxo complex
Badiceanu, Alexandra D.,Garst, Alyson E.,Trubitt, Meredith E.,Nolin, Kristine A.
, p. 67 - 70 (2014/03/21)
A method for synthesizing β- and γ-hydroxy thioethers via addition of unactivated thiols to epoxides and oxetanes has been developed. This reaction is proposed to proceed through an unconventional mode of activation of the heterocycles. The transformation is catalyzed by ReO2I(PPh 3)2 affording β- and γ-hydroxy thioethers in moderate to excellent yield with excellent regioselectivity.
