1147098-21-2

Basic information

• Product Name: tert-butyl (4-(3,3,3-trifluoroprop-1-en-2-yl)phenyl)carbamate
• Synonyms: tert-butyl (4-(3,3,3-trifluoroprop-1-en-2-yl)phenyl)carbamate
• CAS NO: 1147098-21-2
• Molecular Weight: 287.282
• Mol File: 1147098-21-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (4-(3,3,3-trifluoroprop-1-en-2-yl)phenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (4-(3,3,3-trifluoroprop-1-en-2-yl)phenyl)carbamate(1147098-21-2)
• EPA Substance Registry System: tert-butyl (4-(3,3,3-trifluoroprop-1-en-2-yl)phenyl)carbamate(1147098-21-2)

Safety Data

• Hazardous Substances Data: 1147098-21-2(Hazardous Substances Data)

Upstream product

• 1514-82-5 2-bromo-3,3,3-trifluoropropene 
• 380430-49-9 [4-(tert-butoxycarbonylamino)phenyl]boronic acid 

Downstream Products

• 1147098-22-3 tert-Butyl 4-(1,1,1-trifluoropropan-2-yl)phenylcarbamate 

Relevant articles and documents

Redox-Neutral Photocatalytic Cyclopropanation via Radical/Polar Crossover

A benchtop stable, bifunctional reagent for the redox-neutral cyclopropanation of olefins has been developed. Triethylammonium bis(catecholato)iodomethylsilicate can be readily prepared on multigram scale. Using this reagent in combination with an organic photocatalyst and visible light, cyclopropanation of an array of olefins, including trifluoromethyl- and pinacolatoboryl-substituted alkenes, can be accomplished in a matter of hours. The reaction is highly tolerant of traditionally reactive functional groups (carboxylic acids, basic heterocycles, alkyl halides, etc.) and permits the chemoselective cyclopropanation of polyolefinated compounds. Mechanistic interrogation revealed that the reaction proceeds via a rapid anionic 3-exo-tet ring closure, a pathway consistent with experimental and computational data.