114727-43-4

Basic information

• Product Name: NSC 247030
• Synonyms: NSC 247030;SU5201;2H-Indol-2-one, 3-[(3,4-dichlorophenyl)methylene]-1,3-dihydro-
• CAS NO: 114727-43-4
• Molecular Formula: C₁₅H₉Cl₂NO
• Molecular Weight: 290.14406
• EINECS: -0
• Mol File: 114727-43-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 195-197 °C
• Boiling Point: 505.7±50.0 °C(Predicted)
• Appearance: /
• Density: 1.431±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 12.54±0.20(Predicted)
• CAS DataBase Reference: NSC 247030(CAS DataBase Reference)
• NIST Chemistry Reference: NSC 247030(114727-43-4)
• EPA Substance Registry System: NSC 247030(114727-43-4)

Safety Data

• Hazardous Substances Data: 114727-43-4(Hazardous Substances Data)

Usage

General Description

NSC 247030, also known as 4-methylcatechol, is a chemical compound used in various industrial applications. It is a white crystalline solid with a chemical formula of C7H8O2 and a molecular weight of 124.14 g/mol. 4-methylcatechol is primarily used as an intermediate in the synthesis of pharmaceuticals, agricultural chemicals, and other organic compounds. It is also used as a stabilizer in the production of polymers and as a corrosion inhibitor in metal processing. The compound is considered to have low acute toxicity, but its potential long-term effects on human health and the environment have not been extensively studied. Overall, NSC 247030 has a range of industrial uses and applications, but its safety and environmental impact warrant further investigation.

Upstream product

• 59-48-3 2-oxoindole 
• 6287-38-3 3,4-dichlorobenzaldehyde 

Downstream Products

• 114727-53-6 2-{3-[1-(3,4-Dichloro-phenyl)-meth-(E)-ylidene]-2-oxo-2,3-dihydro-indol-1-yl}-propionic acid benzyl ester 
• 114727-48-9 cis-3-(3,4-dichlorobenzylidene)oxindole-1-acetic acid benzyl ester 

Relevant articles and documents

Facile synthesis of 3-arylidene-1,3-dihydroindol-2-ones catalyzed by brnsted acidic ionic liquids

A series of 3-arylidene-1,3-dihydroindol-2-one derivatives were conveniently synthesized by the condensation of aromatic aldehydes with 1,3-dihydroindol-2-one using brnsted acidic ionic liquids as dual solvent-catalyst. This method has the advantages of s

Synthesis and aldose reductase inhibitory activity of substituted 2(1H)-benzimidazolone- and oxindole-1-acetic acids

Potent in vitro inhibition of the enzyme aldose reductase (AR) was observed with several members of a series of 3-alkylated 2(1H)-benzimidazolone-1-acetic acids, as well as with analogs from a structurally-related series of oxindole-1-acetic acids with 3-alkyl or 3-alkylidene substituents.Intrinsic activity against AR was, in general, greatest in compounds from the second series, especially with analogs which containalkylidene side chains, with typical IC50 values of 1 μM.However, in streptozotocindiabetic rat model, the best compounds from either series failedto prevent sorbitol accumulation in lens or sciatic nerve to the degree observed with AR inhibitors such as ponalrestat or zopolrestat. aldose reductase / diabetes / 2(1H)-benzimidazolone-1-acetic acid / oxindole-1-acetic acid