114744-87-5

Upstream product

• 925-90-6 ethylmagnesium bromide 
• 109075-73-2 benzyl (S)-[1-(N-methoxy-N-methylamino)-4-methyl-1-oxopentan-2-yl]carbamate 

Downstream Products

• 114744-95-5 (4S,5S)-5-Ethyl-4-isopropyl-oxazolidin-2-one 
• 114744-99-9 (4S,5R)-5-Ethyl-4-isopropyl-oxazolidin-2-one 
• 114744-91-1 ((1S,2R)-2-Hydroxy-1-isopropyl-butyl)-carbamic acid benzyl ester 

Relevant academic research and scientific papers

A NEW FACILE DIASTEREOCONVERSION OF 2-AMINO ALCOHOLS INVOLVING A NOVEL CYCLOCARBAMATION

A new practical method for diastereoconversion of 2-amino alcohols was performed by treatment on N-Cbz- derivatives with trifluoromethanesulfonic anhydride or thionyl chloride, followed by ring cleavage of the resulting oxazolidin-2-ones

COLLAGENASE INHIBITOR

Compounds having inhibitory activity against inhibitory activity against type IV collagenase and are useful as angiogenesis, cancer infiltration or cancer metastasis inhibitors. The compounds have the formula: STR1 in which R 1 represents a group of formula:--OR. sup.3 (wherein R 3 represents a hydrogen atom or an alkyl group), --NR 4 R 5 (wherein R 4 and R 5 each represents a hydrogen atom, an alkyl or alkoxy group),--NHCH(R 6 COR 7 (wherein R 6 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, and R 7 represents an alkyl group),--NHCH(R 6)COOR. sup.8 (wherein R 8 represents an alkyl group) or--NHCH(R 6)CONR 9 R 10 (wherein R 9 and R 10 each represents a hydrogen atom or an alkyl group, or NR 9 R 10 together represent a heterocyclic ring group); andR 2 represents a hydrogen atom, an alkyl or aralkyl group.