114745-26-5 Usage
Description
5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine is a guanosine derivative characterized by its unique structural features, including an oxime opening at the 5' position and a methylation at the 2' position. This nucleoside has demonstrated an affinity for tissues in chemotactic assays and is known for its powdery chemical properties.
Uses
Used in Biochemical and Nanotechnology Studies:
5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine is used as a key component in the preparation of synthetic RNA derivatives. These derivatives, such as native-like crosslinked duplex RNA, are essential for various biochemical and nanotechnology research applications, enabling the study of RNA structure, function, and interactions at a molecular level.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine is utilized for its potential therapeutic applications. Its unique structure and affinity for tissues make it a promising candidate for the development of new drugs targeting specific biological pathways or receptors.
Used in Research and Development:
5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine is also used in research and development settings to explore its potential in various scientific applications. This includes studying its interactions with biological molecules, understanding its role in cellular processes, and investigating its potential as a therapeutic agent for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 114745-26-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,7,4 and 5 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 114745-26:
(8*1)+(7*1)+(6*4)+(5*7)+(4*4)+(3*5)+(2*2)+(1*6)=115
115 % 10 = 5
So 114745-26-5 is a valid CAS Registry Number.
114745-26-5Relevant articles and documents
An efficient multigram synthesis of monomers for the preparation of novel oligonucleotides containing isosteric non-phosphorous backbones
Dimock, Stuart,Bhat, Balkrishen,Peoc'h, Didier,Sanghvi, Yogesh S.,Swayze, Eric E.
, p. 1629 - 1632 (2007/10/03)
The facile preparation of two novel classes of nucleoside analogs for the inclusion as dimeric non-phosphorous containing subunits in chime fie backbones has been accomplished. The concise preparation of 3'- formylnucleosides and 5'-O-(N-methylhydroxylamino)-nucleosides is reported.