114751-35-8Relevant articles and documents
PREPARATION OF NEW CHIRAL PYRROLIDINEBISPHOSPHINES AS HIGHLY EFFECTIVE LIGANDS FOR CATALYTIC ASYMMETRIC SYNTHESIS OF R-(-)-PANTOLACTONE
Takahashi, Hisashi,Hattori, Masaaki,Chiba, Mitsuo,Morimoto, Toshiaki,Achiwa, Kazuo
, p. 4477 - 4480 (1986)
New chiral pyrrolidinephosphines, MSCPM, PCPM and BCPM, were prepared.Among them, BCPM was found to be most effective ligand for catalytic asymmetric synthesis of R-(-)-pantolactone
Preparations of chiral pyrrolidinebisphosphines bearing two different types of phosphino groups and their use in efficient catalytic asymmetric hydrogenation
Morimoto,Takahashi,Achiwa
, p. 481 - 488 (2007/10/02)
Chiral pyrrolidinebisphosphine ligands, (2S-cis)-BCPM and (2S-cis)-BCPP, bearing two different types of phosphino groups, a dicyclohexylphosphino group and a diphenylphosphino group, were designed and prepared on the basis of our design concept for developing highly efficient ligands. The validity of the concept was confirmed experimentally in the asymmetric hydrogenation of ketopantolactone using neutral rhodium(I) complexes of BCPM. BCPP, BPPM, and BCCP. The rhodium(I) complex of (2S-cis)-BCPM was found to be the most effective catalyst (substrate/catalyst >ca. 104, >90% ee (R)).