114767-66-7

Upstream product

• 142717-42-8 Propyl (R,S)-2-<4-(benzyloxy)phenoxy>propanoate 
• 103-16-2 4-Benzyloxyphenol 
• 59058-37-6 (R,S)-2-<4-(Benzyloxy)phenoxy>propanoic acid 
• 114438-71-0 2-bromopropionic acid propyl ester 
• 123-31-9 hydroquinone 
• 1569-03-5 2-chloro-propionic acid propyl ester 
• 100667-08-1 2-(4-benzyloxy-phenoxy)-propionyl chloride 

Downstream Products

• 71701-89-8 propyl 2-[4-(3-chloro-5-chlorodifluoromethyl-2-pyridyloxy)phenoxy]propionate 
• 85072-18-0 n-propyl 2-[4-(indan-2-yl-oxy)phenoxy]propionate 
• 85072-19-1 n-propyl 2-[4-(tetralin-2-yloxy)phenoxy] propionate 
• 950829-46-6 5-(2-fluorophenyl)-3-methylthio-1-phenyl-6-[4-(1-propoxycarbonylethoxy)]phenoxypyrazolo[3,4-d]pyrimidin-4-one 
• 950829-47-7 5-(4-fluorophenyl)-3-methylthio-1-phenyl-6-[4-(1-propoxycarbonylethoxy)]phenoxypyrazolo[3,4-d]pyrimidin-4-one 
• 105118-15-8 (S)-2-(4-hydroxyphenoxy)propionic acid 
• 937245-14-2 5-(2-methylphenyl)-3-methylthio-1-phenyl-6-[4-(1-propoxycarbonylethoxy)]phenoxypyrazolo[3,4-d]pyrimidin-4-one 
• 937245-13-1 C₃₀H₂₇ClN₄O₅S 
• 937245-12-0 C₃₀H₂₈N₄O₅S 

Relevant academic research and scientific papers

Resolution of (R, S)-ethyl-2-(4-hydroxyphenoxy) propanoate using lyophilized mycelium of Aspergillus oryzae WZ007

The mycelium of Aspergillus oryzae WZ007 was successfully developed to kinetic resolution of (R, S)-ethyl-2-(4-hydroxyphenoxy) propanoate ((R, S)-EHPP) for production of (R)-ethyl-2-(4-hydroxyphenoxy) propanoate ((R)-EHPP). The key biocatalytic process parameters (pH, temperature, rotation speed and substrate concentration) were optimized. Under the optimum conditions, the optical purity of (R)-EHPP was improved up to >99% when the conversion was above 49%. A. oryzae WZ007 whole-cell lipase exhibited high reaction capacity, enantioselectivity and good reusability. The tolerable substrate concentration was 0.5 mol/L, and dry mycelium of A. oryzae WZ007 maintains over 80% of its initial activity after eight repeating cycles. Therefore the enzymatic preparation of (R)-EHPP route was suitable for industrial application.

A novel synthesis and herbicidal activity of fluorine-containing pyrazolo[3,4-d]pyrimidin-4-one derivatives

The 6-(4-alkoxycarbonylalkoxy)phenoxy-3-alkylthio-5-(fluoro-substituted)phenyl-1-phenylpyrazolo[3,4-d]pyrimidin-4-ones 6 have been successfully synthesized via a tandem aza-Wittig and annulation reactions of the corresponding iminophosphorances 4, aromatic isocyanate, and substituted phenols 2 in 59-69% isolated yields using actonitrile as solvent. These novel compounds 6 could be oxidized to sulfones 7 by hydrogen peroxide in satisfactory yields (57-93%). Their structures were clearly verified by spectroscopic data (IR, 1H NMR, 13C NMR, MS, Elemental analysis or X-ray diffraction crystallography). The results of preliminary bioassay indicated that these compounds possess herbicidal activity against the root of rape and barnyard grass.

The Synthesis and Transition Temperatures of Novel Low Molar Mass Cholesteric Materials Derived from (R)-2-(4-Hydroxyphenoxy)propanoic Acid

A comprehensive series of (R)-2-(4-substituted-phenoxy)propanoates and (R)-2-(4-substituted-phenoxy)propanonitriles have been prepared.A wide variety of 4-substituents and ester functions have been examined to determine how the position of the chiral centre affects the cholesteric phase formation in these classes of materials; the synthesis of these novel materials, their transition temperatures and a procedure for assessing their optical purity are described and discussed.Mesogenicity is significantly depressed if the chiral centre is placed centrally within the molecule.