114772-08-6

Basic information

• Product Name: 1H-Imidazole-5-methanol, 1-[(4-aminophenyl)methyl]-2-butyl-4-chloro-
• CAS NO: 114772-08-6
• Molecular Formula: C15H20ClN3O
• Molecular Weight: 293.796
• Mol File: 114772-08-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole-5-methanol, 1-[(4-aminophenyl)methyl]-2-butyl-4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-5-methanol, 1-[(4-aminophenyl)methyl]-2-butyl-4-chloro-(114772-08-6)
• EPA Substance Registry System: 1H-Imidazole-5-methanol, 1-[(4-aminophenyl)methyl]-2-butyl-4-chloro-(114772-08-6)

Safety Data

• Hazardous Substances Data: 114772-08-6(Hazardous Substances Data)

Upstream product

• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 79047-41-9 2-n-butyl-4-chloro-5-hydroxymethylimidazole 
• 114799-92-7 2-Butyl-4-chloro-1-[(4-nitrophenyl)methyl]-1H-imidazole-5-methanol 

Downstream Products

• 142219-12-3 N-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]phenyl]-α-oxo-benzeneacetamide 
• 114798-58-2 2-Butyl-4-chloro-5-hydroxymethyl-1-(4-N-phthalimidobenzyl)imidazole 
• 148549-97-7 N-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]phenyl]-α-cyano-benzenepropanamide 
• 142219-07-6 1-{(S)-1-[4-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylmethyl)-phenylcarbamoyl]-2-phenyl-ethyl}-1H-pyrrole-2-carboxylic acid methyl ester 
• 142219-09-8 1-{[4-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylmethyl)-phenylcarbamoyl]-methyl}-1H-pyrrole-2-carboxylic acid methyl ester 

Relevant articles and documents

Nonpeptide angiotensin II receptor antagonists. 1. Synthesis and in vitro structure-activity relationships of 4[[[(1H-pyrrol-1- ylacetyl)amino]phenyl]methyl]imidazole derivatives as angiotensin II receptor antagonists

A novel series of non-biphenylyltetrazole angiotensin II receptor antagonists which contain a 1H-pyrrol-1-ylacetyl residue in place of the benzoyl residue in EXP 6803 have been developed. The receptor binding activity of several members of this new series

AMINO ACID DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST PROPERTIES

This invention relates to novel amino acid derivatives which antagonize the binding of angiotensin II to its receptors. The compounds are useful in the treatment of hypertension, heart failure, glaucoma, and hyperaldosteronism. Methods of making the compounds, novel intermediates useful in the separation of the compounds, compositions containing the compounds and methods of using them are also covered.