79047-41-9

Basic information

• Product Name: (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL
• Synonyms: (2-butyl-4-chloro-1H-iMidazol-5-yl)Methanol;Losartan EP IMpurity A;2-BUTYL-5-CHLORO-4-HYDROXYMETHYLIMIDAZOLE;2-BUTYL-4-CHLORO-5-(HYDROXYMETHYL)IMIDAZOLE;(2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL;RARECHEM AL BD 0887;2-BUTYL-4-CHLORO-5-(HYDROMETHYL)IMIDAZO&;2-N-BUTYL,4-CHLORO-5-HYDROXY METHYL IMIDAZOLE (BCMI)
• CAS NO: 79047-41-9
• Molecular Formula: C₈H₁₃ClN₂O
• Molecular Weight: 188.65
• Product Categories: Heterocyclic Building Blocks;Heterocyclic Compounds;Heterocycles;Halogenated Heterocycles;Heterocyclic Building Blocks;Imidazoles;ImidazolesBuilding Blocks;Building Blocks;Chemical Synthesis;Halogenated Heterocycles
• Mol File: 79047-41-9.mol
• Article Data: 12

Chemical Properties

• Melting Point: 147-151 °C(lit.)
• Boiling Point: 407.7 °C at 760 mmHg
• Flash Point: 200.4 °C
• Appearance: white crystalline solid
• Density: 1.236
• Vapor Pressure: 2.23E-07mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: 2-8°C
• Solubility: Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 11.26±0.10(Predicted)
• CAS DataBase Reference: (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL(79047-41-9)
• EPA Substance Registry System: (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL(79047-41-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 79047-41-9(Hazardous Substances Data)

Usage

Chemical Properties

White Crystalline Solid

Uses

2-Butyl-5-chloroimidazole-4-methanol (Losartan EP Impurity A) is an impurity of Losartan.

InChI:InChI=1/C8H13ClN2O/c1-2-3-4-7-10-6(5-12)8(9)11-7/h12H,2-5H2,1H3,(H,10,11)

Synthetic route

2-n-butyl-4-chloro-1H-imidazol-5-carboxaldehyde (83857-96-9) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
With sodium tetrahydroborate In methanol at 20℃; for 2h;	90%
With hydrogen; magnesium In methanol at 20℃; under 258.574 - 413.718 Torr; for 0.583333h;

5-benzyloxymethyl-2-butyl-4-chloro-1H-imidazole (679412-76-1) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
With methanesulfonic acid In chloroform at 20℃; for 1h;	90%

2-butyl-5-hydroxymethyl-1H-imidazole (68283-19-2) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + 2-butyl-4,5-dichloroimidazole

Conditions	Yield
With N-chloro-succinimide In tetrahydrofuran	A 65% B 10%

1,4-dioxane (123-91-1) + 2-n-butyl-4,5-di-(hydroxymethyl)-1H-imidazole (136317-69-6) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
With N-chloro-succinimide In ethanol	51%

sodium dichloroisocyanurate dihydrate + 2-n-butyl-4,5-di-(hydroxymethyl)-1H-imidazole (136317-69-6) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
In 1,4-dioxane; ethanol	50%

2-butyl-5-hydroxymethyl-1H-imidazole (68283-19-2) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
With N-chloro-succinimide
Multi-step reaction with 2 steps 1: Et3N / tetrahydrofuran; acetonitrile / 2 h / 0 °C 2: 1.) NCS, 2.) Zn, AcOH / 1.) THF, acetonitrile, from -5 deg C to 0 deg C, 0.75 h, 2.) frp, -5 deg C to 0 deg C, 1.5 h View Scheme
With N-chloro-succinimide In water; ethyl acetate

2-Butyl-5-trimethylsilanyloxymethyl-1H-imidazole (153258-24-3) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + 2-Butyl-4,5-dichloro-4-trimethylsilanyloxymethyl-4H-imidazole

Conditions	Yield
With N-chloro-succinimide; acetic acid; zinc 1.) THF, acetonitrile, from -5 deg C to 0 deg C, 0.75 h, 2.) frp, -5 deg C to 0 deg C, 1.5 h; Yield given. Multistep reaction. Title compound not separated from byproducts;

N-(2-benzyloxy-1-cyanoethyl)pentanamide (679412-75-0) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
Multi-step reaction with 2 steps 1: 81 percent / CCl4; PPh3 / acetonitrile / 4 h / 45 °C 2: 90 percent / methanesulfonic acid / CHCl3 / 1 h / 20 °C View Scheme

methyl pentanimidate (57246-71-6) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
Multi-step reaction with 2 steps 1.1: NaOH / H2O; methanol; toluene 1.2: 55 percent / POCl3 / toluene / 2 h / 100 °C 2.1: 90 percent / NaBH4 / methanol / 2 h / 20 °C View Scheme

ethyl 2-butyl-1H-imidazole-4(5)carboxylate (148990-06-1) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
Multi-step reaction with 2 steps 1: 88 percent / DIBAL / toluene 2: NCS View Scheme

ethyl methyl ether (540-67-0) + 2-butyl-5-hydroxymethyl-1H-imidazole (68283-19-2) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
With N-chloro-succinimide In tetrahydrofuran; diethyl ether	16 g (52%)

sode de l'acide trichloroisocyanurique (2893-78-9) + 2-n-butyl-4,5-di-(hydroxymethyl)-1H-imidazole (136317-69-6) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
In 1,4-dioxane; ethanol

N-chloro-succinimide (128-09-6) + 2-butyl-5-hydroxymethyl-1H-imidazole (68283-19-2) → 2-butyl-4,5-10 dichloroimidazole + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
In tetrahydrofuran; 2-methoxy-ethanol; water

2-methoxy-ethanol (109-86-4) + 2-butyl-5-hydroxymethyl-1H-imidazole (68283-19-2) → 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9)

Conditions	Yield
With N-chloro-succinimide In 1,4-dioxane; water; ethyl acetate

(NH4)2 Ce(NO3)6 + dichloromethane (75-09-2) + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) → 2-n-butyl-4-chloro-1H-imidazol-5-carboxaldehyde (83857-96-9)

Conditions	Yield
With potassium hydroxide In water; acetic acid	92%
In water; acetic acid

4-hydroxy[1]benzopyran-2-one (1076-38-6) + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + malononitrile (109-77-3) → 2-amino-4-(2-butyl-4-chloro-1H-imidazol-5-yl)-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile

Conditions	Yield
With dimethyl sulfoxide; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In ethyl acetate at 20℃; for 9h;	81%

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + tert-butyldimethylsilyl chloride (18162-48-6) → 2-butyl-4-chloro-5-[(t-butyldimethylsilyloxy)methyl]imidazole (137582-52-6)

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide for 3.5h; Ambient temperature;	80%

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + N-(triphenylmethyl)-5-<4'-(bromomethyl)biphenyl-2-yl>tetrazole (133051-88-4) → 2-n-butyl-4-chloro-1-[(2'-(2-triphenylmethyl-2H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl]-1H-imidazole-5-methanol (133909-99-6)

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 10h;	80%

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + β-naphthol (135-19-3) + malononitrile (109-77-3) → 2-amino-4-(2-butyl-4-chloro-1H-imidazol-5-yl)-4H-benzo[g]chromene-3-carbonitrile

Conditions	Yield
With dimethyl sulfoxide; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In ethyl acetate at 20℃; for 12h;	79%

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) → 2-n-butyl-4-chloro-1H-imidazol-5-carboxaldehyde (83857-96-9)

Conditions	Yield
With ammonium cerium(IV) nitrate In acetic acid at 25℃; for 3h;	77%
With 2,2,6,6-tetramethyl-piperidine-N-oxyl; iodine; sodium hydrogencarbonate In water; toluene at 20℃; for 16h;	690 mg
With oxygen; Pt/Bi on graphite In methanol at 60℃; under 2250.23 Torr; for 6h; Product distribution; Further Variations:; Reagents;
With manganese dioxide In dichloromethane	12.81 g (86%)

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + malononitrile (109-77-3) + recorcinol (108-46-3) → 2-amino-4-(2-butyl-4-chloro-1H-imidazol-5-yl)-7-hydroxy-4H-chromene-3-carbonitrile

Conditions	Yield
With dimethyl sulfoxide; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In ethyl acetate at 20℃; for 14h;	74%

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile (114772-54-2) → 2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)-methyl]-5-(hydroxymethyl)imidazole (114772-55-3)

Conditions	Yield
Stage #1: 2-n-butyl-4-chloro-5-hydroxymethylimidazole With sodium methylate In N,N-dimethyl-formamide at 25℃; for 0.5h; Stage #2: 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile In N,N-dimethyl-formamide at 20℃; for 24h;	40%
With sodium methylate 1.) DMF, 25 deg C, 0.25 h, 2.) DMF, 40 deg C, 4 h; Multistep reaction;

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + methyl 4'-(bromomethyl)-3'-fluorobiphenyl-2-carboxylate (138459-24-2) → methyl 3'-fluoro-4'-<<2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl>methyl>biphenyl-2-carboxylate (138459-25-3)

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 3h;	30%

methanol (67-56-1) + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) → 2-butyl-4-chloro-1H-imidazole-5-carboxylic acid,methyl ester (124750-71-6)

Conditions	Yield
With manganese(IV) oxide; sodium cyanide; acetic acid 1.) THF; Multistep reaction;

1,4-bis(bromomethyl)benzene (623-24-5) + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) → [1-(4-Bromomethyl-benzyl)-2-butyl-5-chloro-1H-imidazol-4-yl]-methanol + [3-(4-Bromomethyl-benzyl)-2-butyl-5-chloro-3H-imidazol-4-yl]-methanol

Conditions	Yield
With sodium methylate 1.) methanol, 0 deg C, 2.) DMF, 25 deg C; Multistep reaction;

6-bromomethyl-2-naphthalenecarbonitrile (56358-46-4) + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) → 6-(2-Butyl-5-chloro-4-hydroxymethyl-imidazol-1-ylmethyl)-naphthalene-2-carbonitrile (135943-07-6) + 2-n-butyl-4-chloro-5-(hydroxymethyl)-1-<(2-cyanonaphthalen-6-yl)methyl>imidazole (135943-02-1)

Conditions	Yield
With sodium hydride 1.) DMF, 25 deg C, 1 h, 2.) DMF, RT, 1 h; Yield given. Multistep reaction. Yields of byproduct given;

4-(bromomethyl)benzaldehyde (51359-78-5) + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) → 4-(2-Butyl-5-chloro-4-hydroxymethyl-imidazol-1-ylmethyl)-benzaldehyde (125665-59-0) + 1-(4-formylbenzyl)-2-butyl-4-chloro-5-hydroxymethylimidazole (114773-11-4)

Conditions	Yield
With sodium methylate 1.) methanol, 0 deg C, 2.) DMF, 25 deg C; Multistep reaction;

methyl 4'-(bromomethyl)-[1,1'-biphenyl]-3-carboxylate (114772-37-1) + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) → 2-butyl-1-<(3'-carbomethoxybiphenyl-4-yl)methyl>-4-chloro-5-(hydroxymethyl)imidazole (114772-41-7)

Conditions	Yield
With sodium methylate 1.) DMF, 25 deg C, 0.25 h, 2.) 40 deg C, 4 h; Yield given. Multistep reaction;

methyl 2-[4-(bromomethyl)benzoyl]benzoate (114772-96-2) + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) → 2-butyl-1-<4-(2-carbomethoxybenzoyl)benzyl>-4-chloro-5-(hydroxymethyl)imidazole (114772-97-3)

Conditions	Yield
With sodium methylate 1.) DMF, 25 deg C, 0.25 h, 2.) 40 deg C, 4 h; Yield given. Multistep reaction;

methyl 2-[4-(bromomethyl)phenoxy]benzoate (30087-38-8) + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) → 2-butyl-4-chloro-1-[4-(2-carbomethoxyphenoxy)benzyl]-5-hydroxymethylimidazole (114772-89-3)

Conditions	Yield
With sodium methylate 1.) DMF, 25 deg C, 0.25 h, 2.) 40 deg C, 4 h; Multistep reaction;

2-(4-Bromomethyl-phenylsulfanyl)-benzoic acid methyl ester + 2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) → 2-[4-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylmethyl)-phenylsulfanyl]-benzoic acid methyl ester

Conditions	Yield
With sodium methylate 1.) DMF, 25 deg C, 0.25 h, 2.) 40 deg C, 4 h; Multistep reaction;

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + methyl 4-(bromomethyl)-3-fluorobenzoate (128577-47-9) → 4-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylmethyl)-3-fluoro-benzoic acid methyl ester (138459-26-4)

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 3h;

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + 4'-bromomethyl-2-nitrobiphenyl (114772-39-3) → 2-butyl-4-chloro-5-(hydroxymethyl)-1-<(2'-nitrobiphenyl-4-yl)methyl>imidazole (124750-43-2)

Conditions	Yield
With sodium methylate 1.) DMF, 25 deg C, 0.25 h, 2.) DMF, 40 deg C, 4 h; Multistep reaction;

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + Methyl 4'-(bromomethyl)biphenyl-2-carboxylate (114772-38-2) → 2-butyl-4-chloro-5-hydroxymethyl-1-[(2'-methoxycarbonyl-1,1'-biphenyl-4-yl)methyl]-1H-imidazole (114772-43-9)

Conditions	Yield
With sodium methylate 1.) DMF, 25 deg C, 0.25 h, 2.) DMF, 40 deg C, 4 h; Yield given. Multistep reaction;

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + 2-(4-Bromomethyl-phenyl)-furan-3-carboxylic acid ethyl ester → 2-[4-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylmethyl)-phenyl]-furan-3-carboxylic acid ethyl ester

Conditions	Yield
With sodium methylate 1.) DMF, 25 deg C, 0.25 h, 2.) DMF, 40 deg C, 4 h; Multistep reaction;

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + methyl 4'-methyl-2',6'-dimethoxy<1,1'-biphenyl>-2-carboxylate (134360-53-5) → 4'-<<2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazolyl>methyl>-2',6'-dimethoxy<1,1'-biphenyl>-2-carboxylic acid methyl ester (134360-55-7) + 4'-<<2-butyl-4-(hydroxymethyl)-5-chloro-1H-imidazolyl>methyl>-2',6'-dimethoxy<1,1'-biphenyl>-2-carboxylic acid methyl ester (134360-56-8)

Conditions	Yield
Yield given. Multistep reaction. Yields of byproduct given;

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + 5-(4'-Bromomethyl-biphenyl-2-yl)-3H-[1,2,3]triazole-4-carbonitrile → 2-butyl-4-chloro-1-<<2'-(5-cyano-1,2,3-triazol-4-yl)biphenyl-4-yl>methyl>-5-(hydroxymethyl)imidazole (125573-80-0)

Conditions	Yield
With sodium methylate 1.) DMF, 25 deg C, 0.25 h, 2.) DMF, 40 deg C, 4 h; Multistep reaction;

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + N-(triphenylmethyl)-5-<4'-(bromomethyl)biphenyl-2-yl>tetrazole (133051-88-4) → 2-n-butyl-4-chloro-1-[(2'-(2-triphenylmethyl-2H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl]-1H-imidazole-5-methanol (133909-99-6) + {2-Butyl-5-chloro-1-[2'-(2-trityl-2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-imidazol-4-yl}-methanol

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide Product distribution; Ambient temperature; various ratios of reagents;
With potassium carbonate In N,N-dimethyl-formamide Ambient temperature;

2-n-butyl-4-chloro-5-hydroxymethylimidazole (79047-41-9) + 3-(4'-Bromomethyl-biphenyl-2-yl)-5-trifluoromethyl-4-trityl-4H-[1,2,4]triazole → {2-Butyl-5-chloro-3-[2'-(5-trifluoromethyl-4-trityl-4H-[1,2,4]triazol-3-yl)-biphenyl-4-ylmethyl]-3H-imidazol-4-yl}-methanol

Conditions	Yield
With sodium methylate 1.) DMF, 25 deg C, 0.25 h, 2.) DMF, 40 deg C, 4 h; Multistep reaction;

Upstream product

• 128-09-6 N-chloro-succinimide 
• 68283-19-2 2-butyl-5-hydroxymethyl-1H-imidazole 
• 68283-19-2 2-n-butyl-4-(hydroxymethyl)imidazole 
• 109-86-4 2-methoxy-ethanol 
• 136317-69-6 2-n-butyl-4,5-di-(hydroxymethyl)-1H-imidazole 
• 2893-78-9 sode de l'acide trichloroisocyanurique 
• 123-91-1 1,4-dioxane 
• 540-67-0 ethyl methyl ether 
• 148990-06-1 ethyl 2-butyl-1H-imidazole-4⁽⁵⁾carboxylate 
• 57246-71-6 methyl pentanimidate 
• 679412-75-0 N-(2-benzyloxy-1-cyanoethyl)pentanamide 
• 679412-76-1 5-benzyloxymethyl-2-butyl-4-chloro-1H-imidazole 
• 83857-96-9 2-n-butyl-4-chloro-1H-imidazol-5-carboxaldehyde 
• 153258-24-3 2-Butyl-5-trimethylsilanyloxymethyl-1H-imidazole 

Downstream Products

• 125665-60-3 [2-Butyl-5-chloro-1-(4-methoxy-benzyl)-1H-imidazol-4-yl]-methanol 
• 125665-24-9 [2-Butyl-5-chloro-3-(4-methoxy-benzyl)-3H-imidazol-4-yl]-methanol 
• 83857-96-9 2-n-butyl-4-chloro-1H-imidazol-5-carboxaldehyde 
• 148990-07-2 2-Butyl-5-chloro-3-(2-oxo-2-phenyl-ethyl)-3H-imidazole-4-carboxylic acid methyl ester 
• 148990-08-3 2-Butyl-5-chloro-3-(2-hydroxy-2-phenyl-ethyl)-3H-imidazole-4-carboxylic acid methyl ester 
• 148990-09-4 2-Butyl-5-chloro-3-(2-hydroxy-2-phenyl-ethyl)-3H-imidazole-4-carboxylic acid 
• 148549-84-2 1-{(S)-1-[4-(2-Butyl-4-chloro-5-methoxycarbonylmethyl-imidazol-1-ylmethyl)-phenylcarbamoyl]-2-phenyl-ethyl}-1H-pyrrole-3-carboxylic acid ethyl ester 
• 142219-20-3 (S) Methyl 2-butyl-5-chloro-3-[[4-[[2-[2(methoxycarbonyl)-1H-pyrrol-1-yl]-1-oxo-3-phenylpropyl]amino]phenyl]methyl]-3H-imidazole-4-propanoate 
• 148549-75-1 (S) Methyl 2-butyl-5-chloro-3-[[4-[[2-[2-(methoxycarbonyl)-1H-pyrrol-1-yl]-1-oxo-3-phenylpropyl] amino]phenyl]methyl]-3H-imidazole 4-acetate 
• 142219-16-7 (R,S)-methyl 2-butyl-5-chloro-3-<<4-<<2-<2-(methoxycarbonyl)-1H-pyrrol-1-yl>-1-oxo-3-(2-thienyl)propyl>amino>phenyl>methyl>-3H-imidazole-4-acetate 
• 142219-07-6 1-{(S)-1-[4-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylmethyl)-phenylcarbamoyl]-2-phenyl-ethyl}-1H-pyrrole-2-carboxylic acid methyl ester 
• 148549-86-4 (2-Butyl-5-chloro-3-{4-[(S)-2-(2-methyl-pyrrol-1-yl)-3-phenyl-propionylamino]-benzyl}-3H-imidazol-4-yl)-acetic acid methyl ester 

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