114774-39-9Relevant academic research and scientific papers
A Simple and Broadly Applicable C?N Bond Forming Dearomatization Protocol Enabled by Bifunctional Amino Reagents
Ma, Xiaofeng,Farndon, Joshua J.,Young, Tom A.,Fey, Natalie,Bower, John F.
, p. 14531 - 14535 (2017)
A C?N bond forming dearomatization protocol with broad scope is outlined. Specifically, bifunctional amino reagents are used for sequential nucleophilic and electrophilic C?N bond formations, with the latter effecting the key dearomatization step. Using t
Transition Metal Free C-N Bond Forming Dearomatizations and Aryl C-H Aminations by in Situ Release of a Hydroxylamine-Based Aminating Agent
Farndon, Joshua J.,Ma, Xiaofeng,Bower, John F.
supporting information, p. 14005 - 14008 (2017/10/17)
We outline a simple protocol that accesses directly unprotected secondary amines by intramolecular C-N bond forming dearomatization or aryl C-H amination. The method is dependent on the generation of a potent electrophilic aminating agent released by in situ deprotection of O-Ts activated N-Boc hydroxylamines.
Design of chiral N-triflyl phosphoramide as a strong chiral Bronsted acid and its application to asymmetric Diels-Alder reaction
Nakashima, Daisuke,Yamamoto, Hisashi
, p. 9626 - 9627 (2007/10/03)
A highly reactive and acidic chiral Bronsted acid catalyst, chiral N-triflyl phosphoramide, was developed. Highly enantioselective Diels-Alder reaction of α,β-unsaturated ketone with silyloxydiene was demonstrated using this chiral Bronsted acid catalyst. Copyright
Inhibitor of ribonucleotide reductase of herpes viruses
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, (2008/06/13)
A series of substituted peptides have been found to possess antiviral potency - specifically against herpes viruses - by selectively inhibiting the viral ribonucleotide reductase enzyme.
