501-97-3Relevant articles and documents
Chemical constituents from Ginkgo biloba leaves and their cytotoxicity activity
Shu, Penghua,Sun, Mengyuan,Li, Junping,Zhang, Lingxiang,Xu, Haichang,Lou, Yueyue,Ju, Zhiyu,Wei, Xialan,Wu, Wenming,Sun, Na
, p. 269 - 274 (2020)
One novel neoligan glucoside, Ginkgoside B (1), and one new glucose ester, 6-O-(4-hydroxyhydrocinnamoyl)-d-glucopyranose (2), along with nine known compounds (3–11) were isolated from the ethanol extract of Ginkgo biloba leaves. Their structures were elucidated by combination of spectroscopic analyses and alkaline methanolysis. The absolute configuration of compound 1 was determined by single-crystal X-ray diffraction. All the isolated compounds were evaluated for their cytotoxicity activities, and compound 11 exhibited IC50 values of 36.20 and 58.95?μM against 5637 and HeLa cell lines, respectively.
Isolation and characterization of glycosidic tyrosinase inhibitors from typhonium giganteum rhizomes
Shu, Penghua,Zhu, Huiqing,Liu, Wanrong,Zhang, Lingxiang,Li, Junping,Yu, Mengzhu,Fei, Yingying,Cai, Shujing,Li, Ruihua,Wei, Xialan,Yi, Wenhan,Xiao, Fugang
, p. 380 - 387 (2021/06/02)
A new hydrocinnamoyl glucoside, 1-O-(4-hydroxyhydrocinnamoyl)-β-D-glucopyranose (1), together with fifteen known glycosides, including two phenylethanoid glycosides (2–3), two cinnamoyl glycosides (4–5), six phenolic glycosides (6–11), one lignan glycoside (12) and four megastigmane glycosides (13–16) were isolated from a 95% EtOH extract of the Typhonium giganteum rhizomes. The sixteen glycosides were structurally characterized by NMR, HRESIMS, enzymatic hydrolysis and comparison with literature. Upon evaluating inhibitory activities of compounds 1–16 against mushroom tyrosinase at 25 μM, compounds 10 and 11 exhibited obvious inhibitory activities, with %inhibition values of 20.94±0.59%, 23.28±1.09%, respectively, with arbutin used as the positive control (26.21±0.58%).
Copper and L-(?)-quebrachitol catalyzed hydroxylation and amination of aryl halides under air
Bao, Xuefei,Chen, Guoliang,Dong, Jinhua,Du, Fangyu,Li, Hui,Liang, Xinjie,Wu, Ying,Zhang, Yongsheng
supporting information, (2020/08/03)
L-(?)-Quebrachitol, a natural product obtained from waste water of the rubber industry, was utilized as an efficient ligand for the copper-catalyzed hydroxylation and amination of aryl halides to selectively give phenols and aryl amines in water or 95percent ethanol. In addition, the hydroxylation of 2-chloro-4-hydroxybenzoic acid was validated on a 100-g scale under air.