1148-48-7

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 7-chloro-2-phenyl-
• CAS NO: 1148-48-7
• Molecular Formula: C15H9ClO2
• Molecular Weight: 256.688
• Mol File: 1148-48-7.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 7-chloro-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 7-chloro-2-phenyl-(1148-48-7)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 7-chloro-2-phenyl-(1148-48-7)

Safety Data

• Hazardous Substances Data: 1148-48-7(Hazardous Substances Data)

Upstream product

• 2420-26-0 4-chlorosalicylaldehyde 
• 20718-17-6 2-(dimethyl(oxo)-λ⁶-sulfaneylidene)-1-phenylethan-1-one 
• 6921-66-0 4-chloro-2-hydroxy acetophenone 
• 65-85-0 benzoic acid 
• 1415385-08-8 1-(4-chloro-2-hydroxyphenyl)-3-phenylprop-2-yn-1-one 
• 98-88-4 benzoyl chloride 
• 1415384-97-2 5-chloro-2-(3-phenylprop-2-ynoyl)phenyl benzoate 
• 54551-50-7 2-acetoxy-4-chlorobenzoic acid chloride 
• 17336-08-2 2-carboxy-5-chlorophenyl acetate 
• 1403475-74-0 1-(2-acetoxy-4-chlorophenyl)-3-phenyl-2-propyn-1-one 
• 13031-39-5 3-chlorophenyl acetate 
• 108980-24-1 2'-acetoxy-4'-chlorochalcone 
• 52923-31-6 (E)-1-(4-chloro-2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 58483-55-9 1-(4-chloro-2-hydroxyphenyl)-3-phenylpropane-1,3-dione 

Downstream Products

• 100954-65-2 7-chloro-2-phenyl-chromen-4-one-hydrazone 
• 139027-54-6 7-Chloro-5-hydroxy-4-oxo-2-phenyl-4H-1-benzopyran 
• 1644565-47-8 7-((4-chlorophenyl)amino)-2-phenyl-4H-chromen-4-one 
• 114368-81-9 5-Chloro-7a-phenyl-1a,7a-dihydro-1H-7-oxa-cyclopropa[b]naphthalen-2-one 

Relevant articles and documents

Divergent synthesis of flavones and flavanones from 2′-hydroxydihydrochalconesviapalladium(ii)-catalyzed oxidative cyclization

Divergent and versatile synthetic routes to flavones and flavanonesviaefficient Pd(ii) catalysis are disclosed. These Pd(ii) catalyses expediently provide a variety of flavones and flavanones from 2′-hydroxydihydrochalcones as common intermediates, depending on oxidants and additives,viadiscriminate oxidative cyclization sequences involving dehydrogenation, respectively, in a highly atom-economic manner.

Rh(III)-Catalyzed Aldehydic C?H Functionalization Reaction between Salicylaldehydes and Sulfoxonium Ylides

A novel aldehydic C?H functionalization reaction between salicylaldehydes and sulfoxonium ylides has been developed under rhodium(III) catalysis, affording coupling products in moderate to good yields. A plausible mechanism involving aldehydic C(sp2)?H activation by rhodium(III) and rhodium(III) catalyzed carbene insertion is also proposed. It was also found that the aldehydic C?H functionalization followed by dehydrative cyclization was able to produce flavonoids in one-pot. (Figure presented.).

Divergent synthesis of flavones and aurones via base-controlled regioselective palladium catalyzed carbonylative cyclization

A regioselective approach for construction of 5-membered and 6-membered flavonoid is established by Pd catalyzed carbonylative cyclization of 2-iodophenol with terminal alkynes using different amine bases under mild reaction condition. The catalytic experiments found that piperazine preferentially accelerate 6-endo cyclization, and triethylamine mediated Pd catalyzed 5-exo cyclization. Under optimized reaction condition, Pd catalyzed carbonylative protocol successfully applied for the diverse structures of 39 examples in good to excellent yield and regioselectivity.