1148001-01-7

Basic information

• Product Name: (3R,5R)-3,5-bis(4-chlorophenyl)-3-(hydroxymethyl)heptan-4-one
• Synonyms: (3R,5R)-3,5-bis(4-chlorophenyl)-3-(hydroxymethyl)heptan-4-one
• CAS NO: 1148001-01-7
• Molecular Weight: 365.299
• Mol File: 1148001-01-7.mol

Chemical Properties

• CAS DataBase Reference: (3R,5R)-3,5-bis(4-chlorophenyl)-3-(hydroxymethyl)heptan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5R)-3,5-bis(4-chlorophenyl)-3-(hydroxymethyl)heptan-4-one(1148001-01-7)
• EPA Substance Registry System: (3R,5R)-3,5-bis(4-chlorophenyl)-3-(hydroxymethyl)heptan-4-one(1148001-01-7)

Safety Data

• Hazardous Substances Data: 1148001-01-7(Hazardous Substances Data)

Upstream product

• 1148000-93-4 (S,Z)-3-(4-chlorophenyl)-4-(1-(4-chlorophenyl)propylidene)-3-ethyloxetan-2-one 

Relevant articles and documents

Asymmetric dimerization of disubstituted ketenes catalyzed by N-heterocyclic carbenes

A series of chiral N-heterocyclic carbenes (NHCs), derived from L-pyrogutamic acid, were found to be efficient catalysts for the asymmetric dimerization of alkylarylketenes to give the corresponding α-quaternary β-alkylidenyl-β-lactones in good yields with up to 97% ee. A chiral NHC with a proximal hydroxy group is superior in comparison with the corresponding NHC with its hydroxy group protected.