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1148008-01-8

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1148008-01-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1148008-01-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,8,0,0 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1148008-01:
(9*1)+(8*1)+(7*4)+(6*8)+(5*0)+(4*0)+(3*8)+(2*0)+(1*1)=118
118 % 10 = 8
So 1148008-01-8 is a valid CAS Registry Number.

1148008-01-8Downstream Products

1148008-01-8Relevant articles and documents

Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3-Kinase δ through a Deconstruction and Regrowth Approach

Barton, Nick,Convery, Máire,Cooper, Anthony W. J.,Down, Kenneth,Hamblin, J. Nicole,Inglis, Graham,Peace, Simon,Rowedder, James,Rowland, Paul,Taylor, Jonathan A.,Wellaway, Natalie

, p. 11061 - 11073 (2019/01/08)

A deconstruction of previously reported phosphoinositide 3-kinase δ (PI3Kδ) inhibitors and subsequent regrowth led to the identification of a privileged fragment for PI3Kδ, which was exploited to deliver a potent, efficient, and selective lead series with a novel binding mode observed in the PI3Kδ crystal structure.

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