114820-10-9

Upstream product

• 31664-87-6 2-cyano-1,3-dimethyl-5-nitrobenzene 
• 67083-22-1 N-(2,6-dimethyl-4-nitrophenyl)-4-methylbenzenesulfonamide 
• 4703-15-5 N-(2,6-dimethylphenyl)-4-methylbenzenesulfonamide 
• 87-62-7 2,6-dimethylaniline 
• 16947-63-0 2,6-dimethyl-4-nitroaniline 
• 117832-15-2 4-iodo-3,5-dimethylaniline 

Downstream Products

• 269055-40-5 4-[[5-bromo-4-chloro-6-[(4-cyano-2,6-dimethylphenyl)amino]-2-pyrimidinyl]amino]benzonitrile 
• 269055-46-1 4-[[5-bromo-6-[(4-cyano-2,6-dimethylphenyl)amino]-2-pyrimidinyl]-amino]benzonitrile 

Relevant academic research and scientific papers

Multi-state molecular shuttling of a pair of [2]rotaxane in response to weak and strong acid and base stimuli

This Letter describes the base- and acid-mediated four-state (partially five-state) translational isomerization of a mixture of two [2]rotaxanes, each containing N-alkylamine and N-arylamine centers as binding sites for threaded crown ethers. Gradual chan

PLASMA KALLIKREIN INHIBITORS AND USES THEREOF

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY

Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK 2 and JAK3, are

13C Nuclear Magnetic Resonance Study on the Nature of Resonance Interactions in 4-Substituted Benzonitriles, Acetophenones, and Methyl Benzoates

The effect of X substituents on the C(α) chemical shift of the CN, COMe, and COOMe groups in 2,6-dimethyl-4-substituted-benzonitriles DM-1, 2,6-dimethyl-4-substituted-acetophenones DM-2, and methyl 2,6-dimethyl-4-substituted-benzoates DM-3 has been studie