114827-20-2

Upstream product

• 65-46-3 CYTIDINE 
• 140679-69-2 2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester 
• 140679-67-0 4-N,5'-O-bis(4,4'-dimethoxytrityl)cytidine 
• 114827-16-6 N⁴-(4,4'-dimethoxytrityl)-1-(3-deoxy-β-D-threo-pentofuranosyl)-cytosine 
• 114827-14-4 3'-O-mesyl-2',5'-di-O-pivaloylcytidine 
• 114827-12-2 N⁴,O^2',O^5'-tripivaloyl-3'-O-mesylcytidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 124-63-0 methanesulfonyl chloride 
• 119722-75-7 1-{(2R,3S,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-hydroxy-tetrahydro-furan-2-yl}-4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-1H-pyrimidin-2-one 
• 114827-15-5 2,2-Dimethyl-propionic acid (2R,3R,4R,5R)-2-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-5-(2,2-dimethyl-propionyloxymethyl)-4-methanesulfonyloxy-tetrahydro-furan-3-yl ester 

Downstream Products

• 114827-21-3 N⁴,O^5'-bis(4,4'-dimethoxytrityl)-1-<(2R)-2-azido-2,3-dideoxy-β-D-glycero-pentofuranosyl>cytosine 

Relevant academic research and scientific papers

General Method for the Synthesis of 2'-Azido-2',3'-dideoxynucleosides by the Use of -Hydride Shift and &β-Elimination Reactions

The title nucleoside (16U, C, G and H) were synthesized from pyrimidine and purine ribonucleosides in about 30percent overall yield in 6 steps via key intermediates, protected 3'-deoxy-arabino-nucleosides, which were obtained by deoxygenative -hydrid

The Synthesis of 2',3'-Dideoxycytidine and Its 2'-Azido Analogue. Applications of the Deoxygenative -Hydride Shift of Sulfonates with Mg(OMe)2-NaBH4

New synthetic routes to the title compounds from cytidine were developed.Key intermediates were prepared by the deoxygenative reduction of 3'-O-mesylcytidine derivatives with the title reagents in a one-pot procedure.