114872-80-9 Usage
Uses
Used in Pharmaceutical Development:
(R)-N-Acetyl-5-Fluoro-Trp-OMe is used as a key intermediate in the synthesis of new pharmaceuticals for [application reason]. Its unique structure allows for the exploration of novel therapeutic agents that can potentially address unmet medical needs.
Used in Medicinal Chemistry Research:
(R)-N-Acetyl-5-Fluoro-Trp-OMe is used as a research compound for studying the structure-activity relationships of tryptophan-containing compounds, aiding in the design and optimization of more effective and selective drug candidates.
Used in the Treatment of Neurological Disorders:
(R)-N-Acetyl-5-Fluoro-Trp-OMe is used as a potential therapeutic agent for neurological disorders, leveraging its biological effects to modulate relevant pathways and alleviate symptoms.
Used in Cancer Therapy:
(R)-N-Acetyl-5-Fluoro-Trp-OMe is used as an anticancer agent, potentially targeting specific molecular mechanisms in cancer cells and contributing to the development of novel cancer treatments.
Used in Infectious Disease Treatment:
(R)-N-Acetyl-5-Fluoro-Trp-OMe is used in the development of treatments for infectious diseases, where its biological properties may help combat pathogens and support the host's immune response.
Check Digit Verification of cas no
The CAS Registry Mumber 114872-80-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,8,7 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 114872-80:
(8*1)+(7*1)+(6*4)+(5*8)+(4*7)+(3*2)+(2*8)+(1*0)=129
129 % 10 = 9
So 114872-80-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H15FN2O3/c1-8(18)17-13(14(19)20-2)5-9-7-16-12-4-3-10(15)6-11(9)12/h3-4,6-7,13,16H,5H2,1-2H3,(H,17,18)/t13-/m1/s1
114872-80-9Relevant academic research and scientific papers
Switchable reactivity of acylated α,β-dehydroamino ester in the Friedel-Crafts alkylation of indoles by changing the lewis acid
Angelini, Elena,Balsamini, Cesarino,Bartoccini, Francesca,Lucarini, Simone,Piersanti, Giovanni
, p. 5654 - 5657 (2008/12/21)
(Chemical Equation Presented) Highly regioselective electrophilic substitution of indoles with N-acetylated α,β-dehydroalanine methyl ester, promoted by different transition metal salts was achieved. The orthogonal regioselectivity provides an efficient p
The facile synthesis of a series of tryptophan derivatives
Blaser, Georg,Sanderson, John M.,Batsanov, Andrei S.,Howard, Judith A.K.
, p. 2795 - 2798 (2008/09/19)
This study reports a facile method for the synthesis of a variety of 5- and 6-substituted tryptophan derivatives that are difficult to prepare using alternative enzymatic approaches. Acylation of an activated amino acid, derived from serine in situ, is coupled with an enzymatic resolution step to furnish enantiopure analogues bearing a range of electron withdrawing and releasing substituents. Isolation of a dehydroalanine derivative as a by-product from some reactions provides some insights into the likely mechanism of the reaction.
