114872-98-9

Usage

Uses

Used in Pharmaceutical Research and Development:
D-2,4-Dichlorophenylalanine is used as a key component in the synthesis of novel drugs, particularly for the treatment of neurological disorders and cancer. Its unique structure allows for the development of targeted therapies with improved efficacy and reduced side effects.
Used in Protein Structure and Function Studies:
D-2,4-Dichlorophenylalanine is used as a valuable tool in understanding the structure and function of proteins. Its incorporation into proteins can provide insights into the role of specific amino acid residues and their interactions with other biomolecules.
Used in Peptide-based Pharmaceutical Preparation:
D-2,4-Dichlorophenylalanine is used as a building block in the preparation of peptide-based pharmaceuticals. Its unique properties can enhance the stability, specificity, and therapeutic potential of peptide drugs, making them more effective in treating various diseases.

Upstream product

• 5472-68-4 rac-2,4-dichloro-Phe 
• 444726-81-2 2-acetamido-3-(2,4-dichlorophenyl)propionic acid 

Downstream Products

• 1109216-76-3 C₁₃H₁₅Cl₂NO₃ 
• 1109216-64-9 C₁₃H₁₅Cl₂NO₂ 
• 1109216-91-2 C₁₄H₁₂Cl₂N₂O₂ 
• 1109216-68-3 C₁₄H₁₇Cl₂NO₂ 
• 1109216-90-1 C₁₅H₁₄Cl₂N₂O₂ 
• 880347-64-8 (R)-2-amino-3-(2,4-dichloro-phenyl)-propionic acid methyl ester hydrochloride 
• 1110540-26-5 C₁₃H₁₅Cl₂NO₄ 

Relevant academic research and scientific papers

Enantioselective scavenging using homogenate of Rhodotorula graminis: a facile preparation of d-amino acid derivatives in enantiopure form

An enantioselective scavenger (ES) comprised homogenate of Rhodotorula graminis containing multiple enzymes can enantioselectively remove l-enantiomer in a racemic mixture of amino acid derivatives (AADs), yielding d-enantiomer in high ee. Thirteen non-proteinogenic AADs were produced in enantiopure d form. The method appears to be an efficient cleaning and preparative strategy which can be applied to the production of d-AADs in high ee by enantioselectively scavenging the 'l-contaminants'.

Asymmetric synthesis of unnatural amino acids and tamsulosin chiral intermediate

An efficient and enantioselective hydrogenation of N-acetylamino phenyl acrylic acids was successfully developed by using ruthenium catalyst. This methodology is important in the field of pharmaceuticals and provides a new process for the preparation of unnatural amino acids and tamsulosin chiral intermediate.