114875-61-5

Upstream product

• 68363-44-0 2-oxo-2-(2-(tritylamino)thiazol-4-yl)acetic acid 
• 501-30-4 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 
• 59281-02-6 5-benzhydryloxy-2-(hydroxymethyl)-pyran-4-one 
• 114875-62-6 5-(benzhydryloxy)-1-hydroxy-2-(hydroxymethyl)pyridin-4(1H)-one 
• 114875-64-8 2-Phthalimidooxymethyl-1,5-dibenzhydryloxy-4-pyridone 
• 908093-98-1 diazodiphenylmethane 

Downstream Products

• 404824-80-2 3-[2-(2-tritylaminothiazol-4-yl)-(Z)-2-{(1,5-dibenzhydryloxy-4-pyridon-2-ylmethoxy)imino}acetamido]-4-carbamoyloxymethyl-2-azetidinone 
• 404824-84-6 3-[2-(2-tritylaminothiazol-4-yl)-(Z)-2-{(1,5-dibenzhydryloxy-4-pyridon-2-ylmethoxy)imino}acetamido]-4-fluoromethyl-2-azetidinone-1-sulfonic acid 
• 187544-45-2 (6S,7S)-7-{2-[(Z)-1,5-Bis-benzhydryloxy-4-oxo-1,4-dihydro-pyridin-2-ylmethoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-(pyridin-4-ylsulfanylmethyl)-4-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 404824-78-8 (3S)-trans-3-[[2-(2-tritylamino)thiazol-4-yl]-(Z)-2-{(1,5-dibenzhydryloxy-4-pyridon-2-ylmethoxy)imino}acetamido]-4-methyl-2-oxoazetidine-1-sulfonic acid 
• 136248-40-3 (6S,7S)-7-{2-[(Z)-1,5-Bis-benzhydryloxy-4-oxo-1,4-dihydro-pyridin-2-ylmethoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-([1,2,3]thiadiazol-5-ylsulfanylmethyl)-4-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 136248-38-9 (6S,7S)-7-{2-[(Z)-1,5-Bis-benzhydryloxy-4-oxo-1,4-dihydro-pyridin-2-ylmethoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-([1,3,4]thiadiazol-2-ylsulfanylmethyl)-4-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 

Relevant academic research and scientific papers

C-3 tetrahydrofuran substituted cephalosporin-siderophore conjugate as well as preparation method and application thereof

The invention discloses a C-3-tetrahydrofuran substituted cephalosporin-siderophore conjugate as well as a preparation method and application of the C-3-tetrahydrofuran substituted cephalosporin-siderophore conjugate. The invention discloses the C-3 tetra

USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS

A pharmaceutical composition, comprising a combination of an antibiotically active compound of the formula (I): with a ?-lactamase inhibitor of one of the formulae (II) to (XIII) are active against Gram-negative bacteria, in particular such bacteria which have become resistant against antibiotics such as aztreonam, carumonam and tigemonam. Optionally the compositions may comprise another ?-lactamase inhibitor of one of the formulae (II) to (XIII), particularly of formula (V) or formula (VI).

3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents

The present invention relates to novel Syn isomers of racemates and optical isomers of 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids of formula (I) and its use in treating the infections caused by gram-negative pathogenic bacteria.